Synthesis of functionalized unsymmetrical 1,3-butadiene-3-yne derivatives from β-halo styrene derivatives and their application in the synthesis of trisubstituted pyridines

Vijayalakshmi Bandi, Veerababurao Kavala, Che Hao Hsu, Ashok Konala, Bharath Kumar Villuri, Trimurtulu Kotipalli, Chun Wei Kuo, Ching Fa Yao

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

An approach for the synthesis of functionalized unsymmetrical 1,3-butadiene-3-yne derivatives is reported starting from β-halo styrene and phenyl acetylene derivatives in the presence of PdCl2 and CuI catalysts. Functional groups such as aldehyde, cyano and ester groups are well tolerated and afford the desired functionalized dienynes. Further, these 1,3-buta-diene-3-yne derivatives are utilized for the synthesis of novel trisubstituted pyridine derivatives.

Original languageEnglish
Pages (from-to)46704-46712
Number of pages9
JournalRSC Advances
Volume7
Issue number74
DOIs
Publication statusPublished - 2017 Jan 1

ASJC Scopus subject areas

  • Chemistry(all)
  • Chemical Engineering(all)

Fingerprint Dive into the research topics of 'Synthesis of functionalized unsymmetrical 1,3-butadiene-3-yne derivatives from β-halo styrene derivatives and their application in the synthesis of trisubstituted pyridines'. Together they form a unique fingerprint.

  • Cite this