Synthesis of 3-arylindole derivatives from nitroalkane precursors

Chia Yu Huang, Chun Wei Kuo, Ashok Konala, Tang Hao Yang, Lyu Lin, Yu Wen Chen, Veerababurao Kavala, Ching Fa Yao

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3 Citations (Scopus)

Abstract

3-Arylindole derivatives were synthesized by Cu(i) catalysed intramolecular Ullmann coupling of 2-bromoarylaminoalkanes. 2-Bromoarylaminoalkanes were synthesized from 2-bromoarylnitroalkanes, which in turn prepared through AlCl3-mediated Friedel-Crafts alkylation of bromo-substituted β-nitrostyrenes and arenes.

Original languageEnglish
Pages (from-to)96049-96056
Number of pages8
JournalRSC Advances
Volume6
Issue number98
DOIs
Publication statusPublished - 2016 Jan 1

ASJC Scopus subject areas

  • Chemistry(all)
  • Chemical Engineering(all)

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  • Cite this

    Huang, C. Y., Kuo, C. W., Konala, A., Yang, T. H., Lin, L., Chen, Y. W., Kavala, V., & Yao, C. F. (2016). Synthesis of 3-arylindole derivatives from nitroalkane precursors. RSC Advances, 6(98), 96049-96056. https://doi.org/10.1039/c6ra21144e