Synthesis of 3-arylindole derivatives from nitroalkane precursors

Chia Yu Huang, Chun Wei Kuo, Ashok Konala, Tang Hao Yang, Lyu Lin, Yu Wen Chen, Veerababurao Kavala, Ching Fa Yao

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

3-Arylindole derivatives were synthesized by Cu(i) catalysed intramolecular Ullmann coupling of 2-bromoarylaminoalkanes. 2-Bromoarylaminoalkanes were synthesized from 2-bromoarylnitroalkanes, which in turn prepared through AlCl3-mediated Friedel-Crafts alkylation of bromo-substituted β-nitrostyrenes and arenes.

Original languageEnglish
Pages (from-to)96049-96056
Number of pages8
JournalRSC Advances
Volume6
Issue number98
DOIs
Publication statusPublished - 2016 Jan 1

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Alkylation
Derivatives
aluminum chloride

ASJC Scopus subject areas

  • Chemistry(all)
  • Chemical Engineering(all)

Cite this

Huang, C. Y., Kuo, C. W., Konala, A., Yang, T. H., Lin, L., Chen, Y. W., ... Yao, C. F. (2016). Synthesis of 3-arylindole derivatives from nitroalkane precursors. RSC Advances, 6(98), 96049-96056. https://doi.org/10.1039/c6ra21144e

Synthesis of 3-arylindole derivatives from nitroalkane precursors. / Huang, Chia Yu; Kuo, Chun Wei; Konala, Ashok; Yang, Tang Hao; Lin, Lyu; Chen, Yu Wen; Kavala, Veerababurao; Yao, Ching Fa.

In: RSC Advances, Vol. 6, No. 98, 01.01.2016, p. 96049-96056.

Research output: Contribution to journalArticle

Huang, CY, Kuo, CW, Konala, A, Yang, TH, Lin, L, Chen, YW, Kavala, V & Yao, CF 2016, 'Synthesis of 3-arylindole derivatives from nitroalkane precursors', RSC Advances, vol. 6, no. 98, pp. 96049-96056. https://doi.org/10.1039/c6ra21144e
Huang CY, Kuo CW, Konala A, Yang TH, Lin L, Chen YW et al. Synthesis of 3-arylindole derivatives from nitroalkane precursors. RSC Advances. 2016 Jan 1;6(98):96049-96056. https://doi.org/10.1039/c6ra21144e
Huang, Chia Yu ; Kuo, Chun Wei ; Konala, Ashok ; Yang, Tang Hao ; Lin, Lyu ; Chen, Yu Wen ; Kavala, Veerababurao ; Yao, Ching Fa. / Synthesis of 3-arylindole derivatives from nitroalkane precursors. In: RSC Advances. 2016 ; Vol. 6, No. 98. pp. 96049-96056.
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