Abstract
Organocatalytic domino Michael-hemiacetalization of β-tetralones with α,β-unsaturated aldehydes is presented. Treatment of β-tetralones with α,β-unsaturated aldehydes in the presence of diphenylprolinol silyl ether gave 2,3,5,6-tetrahydro-1-alkyl/aryl-1H-benzo[f] chromen-3-ol derivatives with high to excellent chemical yields (50-99%) and high levels of enantioselectivities (up to 96% ee).
Original language | English |
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Pages (from-to) | 7510-7516 |
Number of pages | 7 |
Journal | Organic and Biomolecular Chemistry |
Volume | 9 |
Issue number | 21 |
DOIs | |
Publication status | Published - 2011 Nov 7 |
ASJC Scopus subject areas
- Biochemistry
- Physical and Theoretical Chemistry
- Organic Chemistry