Abstract
A one-pot reaction has been devloped for the preparation of 1,2,3-fused indole polyheterocycles by starting from 2-iodobenzamide and 2-iodobenzyl cyanide in the presence of a copper catalyst. The cascade process involves the efficient formation of one C–C and three C–N bonds. A broad substrate scope, good yields, and short reactions times are key features of this strategy.
| Original language | English |
|---|---|
| Pages (from-to) | 1241-1247 |
| Number of pages | 7 |
| Journal | European Journal of Organic Chemistry |
| Volume | 2018 |
| Issue number | 10 |
| DOIs | |
| Publication status | Published - 2018 Mar 14 |
Keywords
- Copper
- Domino reactions
- Nitrogen heterocycles
- Polycycles
- Synthetic methods
ASJC Scopus subject areas
- Physical and Theoretical Chemistry
- Organic Chemistry
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CCDC 1812834: Experimental Crystal Structure Determination
Kavala, V. (Contributor), Yang, Z. (Contributor), Konala, A. (Contributor), Yang, T.-H. (Contributor), Kuo, C.-W. (Contributor), Ruan, J.-Y. (Contributor) & Yao, C.-F. (Contributor), Unknown Publisher, 2018
DOI: 10.5517/ccdc.csd.cc1yvdjq, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc1yvdjq&sid=DataCite
Dataset
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CCDC 1812835: Experimental Crystal Structure Determination
Kavala, V. (Contributor), Yang, Z. (Contributor), Konala, A. (Contributor), Yang, T.-H. (Contributor), Kuo, C.-W. (Contributor), Ruan, J.-Y. (Contributor) & Yao, C.-F. (Contributor), Unknown Publisher, 2018
DOI: 10.5517/ccdc.csd.cc1yvdkr, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccdc.csd.cc1yvdkr&sid=DataCite
Dataset