Abstract
A one-pot reaction has been devloped for the preparation of 1,2,3-fused indole polyheterocycles by starting from 2-iodobenzamide and 2-iodobenzyl cyanide in the presence of a copper catalyst. The cascade process involves the efficient formation of one C–C and three C–N bonds. A broad substrate scope, good yields, and short reactions times are key features of this strategy.
Original language | English |
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Pages (from-to) | 1241-1247 |
Number of pages | 7 |
Journal | European Journal of Organic Chemistry |
Volume | 2018 |
Issue number | 10 |
DOIs | |
Publication status | Published - 2018 Mar 14 |
Keywords
- Copper
- Domino reactions
- Nitrogen heterocycles
- Polycycles
- Synthetic methods
ASJC Scopus subject areas
- Physical and Theoretical Chemistry
- Organic Chemistry