Synthesis and Reactivity toward Acyl Chlorides and Enones of the New Highly Functionalized Copper Reagents RCu(CN)ZnI

Paul Knochel, Ming-Chang P. Yeh, Scott C. Berk, Jason Talbert

Research output: Contribution to journalArticle

604 Citations (Scopus)

Abstract

The new and highly functionalized copper reagents RCu(CN)ZnI obtained from readily available primary and secondary alkylzinc iodides by a transmetalation in THF with the soluble salt, CuCN-2LiX, react in good yields with acyl chlorides and enones, respectively, to afford ketones and 1,4-addition products.

Original languageEnglish
Pages (from-to)2390-2392
Number of pages3
JournalJournal of Organic Chemistry
Volume53
Issue number10
DOIs
Publication statusPublished - 1988 Feb 1
Externally publishedYes

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Iodides
Ketones
Chlorides
Copper
Salts

ASJC Scopus subject areas

  • Organic Chemistry

Cite this

Synthesis and Reactivity toward Acyl Chlorides and Enones of the New Highly Functionalized Copper Reagents RCu(CN)ZnI. / Knochel, Paul; Yeh, Ming-Chang P.; Berk, Scott C.; Talbert, Jason.

In: Journal of Organic Chemistry, Vol. 53, No. 10, 01.02.1988, p. 2390-2392.

Research output: Contribution to journalArticle

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