Synthesis and Reactivity toward Acyl Chlorides and Enones of the New Highly Functionalized Copper Reagents RCu(CN)ZnI

Paul Knochel, Ming Chang P. Yeh, Scott C. Berk, Jason Talbert

Research output: Contribution to journalArticle

604 Citations (Scopus)

Abstract

The new and highly functionalized copper reagents RCu(CN)ZnI obtained from readily available primary and secondary alkylzinc iodides by a transmetalation in THF with the soluble salt, CuCN-2LiX, react in good yields with acyl chlorides and enones, respectively, to afford ketones and 1,4-addition products.

Original languageEnglish
Pages (from-to)2390-2392
Number of pages3
JournalJournal of Organic Chemistry
Volume53
Issue number10
DOIs
Publication statusPublished - 1988 Feb 1

ASJC Scopus subject areas

  • Organic Chemistry

Fingerprint Dive into the research topics of 'Synthesis and Reactivity toward Acyl Chlorides and Enones of the New Highly Functionalized Copper Reagents RCu(CN)ZnI'. Together they form a unique fingerprint.

  • Cite this