Syntheses of indolo[1,2-a]quinazolinone derivatives via palladium catalyzed intramolecular C-H amidation

Trimurtulu Kotipalli, Veerababurao Kavala, Donala Janreddy, Chun Wei Kuo, Ting Shen Kuo, Hsiu Ni Huang, Chiu Hui He, Ching Fa Yao*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

19 Citations (Scopus)

Abstract

The synthesis of indolo[1,2-a]quinazolinone starting from 2-iodobenzamide and indole derivatives is reported. In this two-step procedure, indole is N-arylated with 2-iodobenzamide derivatives via Ullman coupling, followed by an intramolecular C-H amidation using a palladium catalyst.

Original languageEnglish
Pages (from-to)2274-2283
Number of pages10
JournalRSC Advances
Volume4
Issue number5
DOIs
Publication statusPublished - 2014

ASJC Scopus subject areas

  • General Chemistry
  • General Chemical Engineering

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