Syntheses of indolo[1,2-a]quinazolinone derivatives via palladium catalyzed intramolecular C-H amidation

Trimurtulu Kotipalli; Veerababurao Kavala; Donala Janreddy; Chun Wei Kuo; Ting Shen Kuo; Hsiu Ni Huang; Chiu Hui He; Ching Fa Yao

doi:10.1039/c3ra44798g

Syntheses of indolo[1,2-a]quinazolinone derivatives via palladium catalyzed intramolecular C-H amidation

Trimurtulu Kotipalli, Veerababurao Kavala, Donala Janreddy, Chun Wei Kuo, Ting Shen Kuo, Hsiu Ni Huang, Chiu Hui He, Ching Fa Yao^*

^*Corresponding author for this work

Department of Chemistry

Research output: Contribution to journal › Article › peer-review

20 Citations (Scopus)

Abstract

The synthesis of indolo[1,2-a]quinazolinone starting from 2-iodobenzamide and indole derivatives is reported. In this two-step procedure, indole is N-arylated with 2-iodobenzamide derivatives via Ullman coupling, followed by an intramolecular C-H amidation using a palladium catalyst.

Original language	English
Pages (from-to)	2274-2283
Number of pages	10
Journal	RSC Advances
Volume	4
Issue number	5
DOIs	https://doi.org/10.1039/c3ra44798g
Publication status	Published - 2014

ASJC Scopus subject areas

General Chemistry
General Chemical Engineering

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10.1039/c3ra44798g

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title = "Syntheses of indolo[1,2-a]quinazolinone derivatives via palladium catalyzed intramolecular C-H amidation",

abstract = "The synthesis of indolo[1,2-a]quinazolinone starting from 2-iodobenzamide and indole derivatives is reported. In this two-step procedure, indole is N-arylated with 2-iodobenzamide derivatives via Ullman coupling, followed by an intramolecular C-H amidation using a palladium catalyst.",

author = "Trimurtulu Kotipalli and Veerababurao Kavala and Donala Janreddy and Kuo, {Chun Wei} and Kuo, {Ting Shen} and Huang, {Hsiu Ni} and He, {Chiu Hui} and Yao, {Ching Fa}",

year = "2014",

doi = "10.1039/c3ra44798g",

language = "English",

volume = "4",

pages = "2274--2283",

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T1 - Syntheses of indolo[1,2-a]quinazolinone derivatives via palladium catalyzed intramolecular C-H amidation

AU - Kotipalli, Trimurtulu

AU - Kavala, Veerababurao

AU - Janreddy, Donala

AU - Kuo, Chun Wei

AU - Kuo, Ting Shen

AU - Huang, Hsiu Ni

AU - He, Chiu Hui

AU - Yao, Ching Fa

PY - 2014

Y1 - 2014

N2 - The synthesis of indolo[1,2-a]quinazolinone starting from 2-iodobenzamide and indole derivatives is reported. In this two-step procedure, indole is N-arylated with 2-iodobenzamide derivatives via Ullman coupling, followed by an intramolecular C-H amidation using a palladium catalyst.

AB - The synthesis of indolo[1,2-a]quinazolinone starting from 2-iodobenzamide and indole derivatives is reported. In this two-step procedure, indole is N-arylated with 2-iodobenzamide derivatives via Ullman coupling, followed by an intramolecular C-H amidation using a palladium catalyst.

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U2 - 10.1039/c3ra44798g

DO - 10.1039/c3ra44798g

M3 - Article

AN - SCOPUS:84890282150

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JO - RSC Advances

JF - RSC Advances

IS - 5

ER -

Syntheses of indolo[1,2-a]quinazolinone derivatives via palladium catalyzed intramolecular C-H amidation

Abstract

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CCDC 958648: Experimental Crystal Structure Determination

Cite this

Syntheses of indolo[1,2-a]quinazolinone derivatives via palladium catalyzed intramolecular C-H amidation

Abstract

ASJC Scopus subject areas

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Other files and links

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Datasets

CCDC 958648: Experimental Crystal Structure Determination

Cite this