The synthesis of indolo[1,2-a]quinazolinone starting from 2-iodobenzamide and indole derivatives is reported. In this two-step procedure, indole is N-arylated with 2-iodobenzamide derivatives via Ullman coupling, followed by an intramolecular C-H amidation using a palladium catalyst.
ASJC Scopus subject areas
- Chemical Engineering(all)
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Kuo, T. (Contributor), Kotipalli, T. (Contributor), Kavala, V. (Contributor), He, C. (Contributor), Huang, H. (Contributor), Kuo, C. (Contributor), Janreddy, D. (Contributor) & Yao, C. (Contributor), Unknown Publisher, 2014 Jan 1