Syntheses of indolo[1,2-a]quinazolinone derivatives via palladium catalyzed intramolecular C-H amidation

Trimurtulu Kotipalli, Veerababurao Kavala, Donala Janreddy, Chun Wei Kuo, Ting Shen Kuo, Hsiu Ni Huang, Chiu Hui He, Ching-Fa Yao

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16 Citations (Scopus)

Abstract

The synthesis of indolo[1,2-a]quinazolinone starting from 2-iodobenzamide and indole derivatives is reported. In this two-step procedure, indole is N-arylated with 2-iodobenzamide derivatives via Ullman coupling, followed by an intramolecular C-H amidation using a palladium catalyst.

Original languageEnglish
Pages (from-to)2274-2283
Number of pages10
JournalRSC Advances
Volume4
Issue number5
DOIs
Publication statusPublished - 2014 Jan 1

ASJC Scopus subject areas

  • Chemistry(all)
  • Chemical Engineering(all)

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    Kotipalli, T., Kavala, V., Janreddy, D., Kuo, C. W., Kuo, T. S., Huang, H. N., He, C. H., & Yao, C-F. (2014). Syntheses of indolo[1,2-a]quinazolinone derivatives via palladium catalyzed intramolecular C-H amidation. RSC Advances, 4(5), 2274-2283. https://doi.org/10.1039/c3ra44798g