Syntheses of indolo[1,2-a]quinazolinone derivatives via palladium catalyzed intramolecular C-H amidation

Trimurtulu Kotipalli, Veerababurao Kavala, Donala Janreddy, Chun Wei Kuo, Ting Shen Kuo, Hsiu Ni Huang, Chiu Hui He, Ching-Fa Yao

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

The synthesis of indolo[1,2-a]quinazolinone starting from 2-iodobenzamide and indole derivatives is reported. In this two-step procedure, indole is N-arylated with 2-iodobenzamide derivatives via Ullman coupling, followed by an intramolecular C-H amidation using a palladium catalyst.

Original languageEnglish
Pages (from-to)2274-2283
Number of pages10
JournalRSC Advances
Volume4
Issue number5
DOIs
Publication statusPublished - 2014 Jan 1

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Quinazolinones
Palladium
Derivatives
Catalysts
indole

ASJC Scopus subject areas

  • Chemistry(all)
  • Chemical Engineering(all)

Cite this

Syntheses of indolo[1,2-a]quinazolinone derivatives via palladium catalyzed intramolecular C-H amidation. / Kotipalli, Trimurtulu; Kavala, Veerababurao; Janreddy, Donala; Kuo, Chun Wei; Kuo, Ting Shen; Huang, Hsiu Ni; He, Chiu Hui; Yao, Ching-Fa.

In: RSC Advances, Vol. 4, No. 5, 01.01.2014, p. 2274-2283.

Research output: Contribution to journalArticle

Kotipalli, T, Kavala, V, Janreddy, D, Kuo, CW, Kuo, TS, Huang, HN, He, CH & Yao, C-F 2014, 'Syntheses of indolo[1,2-a]quinazolinone derivatives via palladium catalyzed intramolecular C-H amidation', RSC Advances, vol. 4, no. 5, pp. 2274-2283. https://doi.org/10.1039/c3ra44798g
Kotipalli, Trimurtulu ; Kavala, Veerababurao ; Janreddy, Donala ; Kuo, Chun Wei ; Kuo, Ting Shen ; Huang, Hsiu Ni ; He, Chiu Hui ; Yao, Ching-Fa. / Syntheses of indolo[1,2-a]quinazolinone derivatives via palladium catalyzed intramolecular C-H amidation. In: RSC Advances. 2014 ; Vol. 4, No. 5. pp. 2274-2283.
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