Syntheses of furo[3,4-c]coumarins and related furyl coumarin derivatives via intramolecular Wittig reactions

Yeong Jiunn Jang; Siang En Syu; Yu Jhang Chen; Mei Chun Yang; Wenwei Lin

doi:10.1039/c1ob06571h

Syntheses of furo[3,4-c]coumarins and related furyl coumarin derivatives via intramolecular Wittig reactions

Yeong Jiunn Jang, Siang En Syu, Yu Jhang Chen, Mei Chun Yang, Wenwei Lin

Department of Chemistry

Research output: Contribution to journal › Article

36 Citations (Scopus)

Abstract

A new and general strategy for highly functional furo[3,4-c]coumarins and related furyl coumarin derivatives has been developed, which is based on an extraordinarily facile intramolecular Wittig reaction, starting from α,β-unsaturated ketones, tributylphosphine, and acyl chlorides. The phosphorus ylides were proposed to be the key intermediates for constructing the crucial furan ring, leading to a wide variety of substituted furyl coumarins in one step.

Original language	English
Pages (from-to)	843-847
Number of pages	5
Journal	Organic and Biomolecular Chemistry
Volume	10
Issue number	4
DOIs	https://doi.org/10.1039/c1ob06571h
Publication status	Published - 2012 Jan 28

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ASJC Scopus subject areas

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

Cite this

Jang, Y. J., Syu, S. E., Chen, Y. J., Yang, M. C., & Lin, W. (2012). Syntheses of furo[3,4-c]coumarins and related furyl coumarin derivatives via intramolecular Wittig reactions. Organic and Biomolecular Chemistry, 10(4), 843-847. https://doi.org/10.1039/c1ob06571h

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Access to Document

10.1039/c1ob06571h