Syntheses of furo[3,4-c]coumarins and related furyl coumarin derivatives via intramolecular Wittig reactions

Yeong Jiunn Jang, Siang En Syu, Yu Jhang Chen, Mei Chun Yang, Wenwei Lin

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36 Citations (Scopus)


A new and general strategy for highly functional furo[3,4-c]coumarins and related furyl coumarin derivatives has been developed, which is based on an extraordinarily facile intramolecular Wittig reaction, starting from α,β-unsaturated ketones, tributylphosphine, and acyl chlorides. The phosphorus ylides were proposed to be the key intermediates for constructing the crucial furan ring, leading to a wide variety of substituted furyl coumarins in one step.

Original languageEnglish
Pages (from-to)843-847
Number of pages5
JournalOrganic and Biomolecular Chemistry
Issue number4
Publication statusPublished - 2012 Jan 28


ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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