Abstract
A new and general strategy for highly functional furo[3,4-c]coumarins and related furyl coumarin derivatives has been developed, which is based on an extraordinarily facile intramolecular Wittig reaction, starting from α,β-unsaturated ketones, tributylphosphine, and acyl chlorides. The phosphorus ylides were proposed to be the key intermediates for constructing the crucial furan ring, leading to a wide variety of substituted furyl coumarins in one step.
| Original language | English |
|---|---|
| Pages (from-to) | 843-847 |
| Number of pages | 5 |
| Journal | Organic and Biomolecular Chemistry |
| Volume | 10 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - 2012 Jan 28 |
ASJC Scopus subject areas
- Biochemistry
- Physical and Theoretical Chemistry
- Organic Chemistry
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Jang, Y. J., Syu, S. E., Chen, Y. J., Yang, M. C., & Lin, W. (2012). Syntheses of furo[3,4-c]coumarins and related furyl coumarin derivatives via intramolecular Wittig reactions. Organic and Biomolecular Chemistry, 10(4), 843-847. https://doi.org/10.1039/c1ob06571h