Syntheses of furo[3,4-c]coumarins and related furyl coumarin derivatives via intramolecular Wittig reactions

Yeong Jiunn Jang, Siang En Syu, Yu Jhang Chen, Mei Chun Yang, Wenwei Lin

Research output: Contribution to journalArticle

36 Citations (Scopus)

Abstract

A new and general strategy for highly functional furo[3,4-c]coumarins and related furyl coumarin derivatives has been developed, which is based on an extraordinarily facile intramolecular Wittig reaction, starting from α,β-unsaturated ketones, tributylphosphine, and acyl chlorides. The phosphorus ylides were proposed to be the key intermediates for constructing the crucial furan ring, leading to a wide variety of substituted furyl coumarins in one step.

Original languageEnglish
Pages (from-to)843-847
Number of pages5
JournalOrganic and Biomolecular Chemistry
Volume10
Issue number4
DOIs
Publication statusPublished - 2012 Jan 28

Fingerprint

Coumarins
furans
ketones
phosphorus
chlorides
rings
synthesis
Ketones
Phosphorus
Chlorides

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

Cite this

Syntheses of furo[3,4-c]coumarins and related furyl coumarin derivatives via intramolecular Wittig reactions. / Jang, Yeong Jiunn; Syu, Siang En; Chen, Yu Jhang; Yang, Mei Chun; Lin, Wenwei.

In: Organic and Biomolecular Chemistry, Vol. 10, No. 4, 28.01.2012, p. 843-847.

Research output: Contribution to journalArticle

Jang, Yeong Jiunn ; Syu, Siang En ; Chen, Yu Jhang ; Yang, Mei Chun ; Lin, Wenwei. / Syntheses of furo[3,4-c]coumarins and related furyl coumarin derivatives via intramolecular Wittig reactions. In: Organic and Biomolecular Chemistry. 2012 ; Vol. 10, No. 4. pp. 843-847.
@article{37e68552953140e08f6254f4945da85b,
title = "Syntheses of furo[3,4-c]coumarins and related furyl coumarin derivatives via intramolecular Wittig reactions",
abstract = "A new and general strategy for highly functional furo[3,4-c]coumarins and related furyl coumarin derivatives has been developed, which is based on an extraordinarily facile intramolecular Wittig reaction, starting from α,β-unsaturated ketones, tributylphosphine, and acyl chlorides. The phosphorus ylides were proposed to be the key intermediates for constructing the crucial furan ring, leading to a wide variety of substituted furyl coumarins in one step.",
author = "Jang, {Yeong Jiunn} and Syu, {Siang En} and Chen, {Yu Jhang} and Yang, {Mei Chun} and Wenwei Lin",
year = "2012",
month = "1",
day = "28",
doi = "10.1039/c1ob06571h",
language = "English",
volume = "10",
pages = "843--847",
journal = "Organic and Biomolecular Chemistry",
issn = "1477-0520",
publisher = "Royal Society of Chemistry",
number = "4",

}

TY - JOUR

T1 - Syntheses of furo[3,4-c]coumarins and related furyl coumarin derivatives via intramolecular Wittig reactions

AU - Jang, Yeong Jiunn

AU - Syu, Siang En

AU - Chen, Yu Jhang

AU - Yang, Mei Chun

AU - Lin, Wenwei

PY - 2012/1/28

Y1 - 2012/1/28

N2 - A new and general strategy for highly functional furo[3,4-c]coumarins and related furyl coumarin derivatives has been developed, which is based on an extraordinarily facile intramolecular Wittig reaction, starting from α,β-unsaturated ketones, tributylphosphine, and acyl chlorides. The phosphorus ylides were proposed to be the key intermediates for constructing the crucial furan ring, leading to a wide variety of substituted furyl coumarins in one step.

AB - A new and general strategy for highly functional furo[3,4-c]coumarins and related furyl coumarin derivatives has been developed, which is based on an extraordinarily facile intramolecular Wittig reaction, starting from α,β-unsaturated ketones, tributylphosphine, and acyl chlorides. The phosphorus ylides were proposed to be the key intermediates for constructing the crucial furan ring, leading to a wide variety of substituted furyl coumarins in one step.

UR - http://www.scopus.com/inward/record.url?scp=84555196120&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84555196120&partnerID=8YFLogxK

U2 - 10.1039/c1ob06571h

DO - 10.1039/c1ob06571h

M3 - Article

C2 - 22130868

AN - SCOPUS:84555196120

VL - 10

SP - 843

EP - 847

JO - Organic and Biomolecular Chemistry

JF - Organic and Biomolecular Chemistry

SN - 1477-0520

IS - 4

ER -