Surface functional DNA density control by programmable molecular defects

Chong You Chen; Chang Ming Wang; Pai Shan Chen; Wei Ssu Liao

doi:10.1039/c7cc09908h

Surface functional DNA density control by programmable molecular defects

Chong You Chen, Chang Ming Wang, Pai Shan Chen, Wei Ssu Liao^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

11 Citations (Scopus)

Abstract

Programmable surface-patterned functional DNA density is achieved via manipulation of molecular-level defects through chemical lift-off lithography. Artificial SAM defects are well-tunable by a contact-induced reaction, enabling molecular environment guidance and DNA insertion to be spatially and quantitatively addressable. This straightforward molecular density control creates an advanced avenue toward fabricating multiplexed bioactive substrates.

Original language	English
Pages (from-to)	4100-4103
Number of pages	4
Journal	Chemical Communications
Volume	54
Issue number	33
DOIs	https://doi.org/10.1039/c7cc09908h
Publication status	Published - 2018
Externally published	Yes

ASJC Scopus subject areas

Catalysis
Electronic, Optical and Magnetic Materials
Ceramics and Composites
General Chemistry
Surfaces, Coatings and Films
Metals and Alloys
Materials Chemistry

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title = "Surface functional DNA density control by programmable molecular defects",

abstract = "Programmable surface-patterned functional DNA density is achieved via manipulation of molecular-level defects through chemical lift-off lithography. Artificial SAM defects are well-tunable by a contact-induced reaction, enabling molecular environment guidance and DNA insertion to be spatially and quantitatively addressable. This straightforward molecular density control creates an advanced avenue toward fabricating multiplexed bioactive substrates.",

author = "Chen, {Chong You} and Wang, {Chang Ming} and Chen, {Pai Shan} and Liao, {Wei Ssu}",

note = "Publisher Copyright: {\textcopyright} 2018 The Royal Society of Chemistry.",

year = "2018",

doi = "10.1039/c7cc09908h",

language = "English",

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AU - Chen, Chong You

AU - Wang, Chang Ming

AU - Chen, Pai Shan

AU - Liao, Wei Ssu

PY - 2018

Y1 - 2018

N2 - Programmable surface-patterned functional DNA density is achieved via manipulation of molecular-level defects through chemical lift-off lithography. Artificial SAM defects are well-tunable by a contact-induced reaction, enabling molecular environment guidance and DNA insertion to be spatially and quantitatively addressable. This straightforward molecular density control creates an advanced avenue toward fabricating multiplexed bioactive substrates.

AB - Programmable surface-patterned functional DNA density is achieved via manipulation of molecular-level defects through chemical lift-off lithography. Artificial SAM defects are well-tunable by a contact-induced reaction, enabling molecular environment guidance and DNA insertion to be spatially and quantitatively addressable. This straightforward molecular density control creates an advanced avenue toward fabricating multiplexed bioactive substrates.

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U2 - 10.1039/c7cc09908h

DO - 10.1039/c7cc09908h

M3 - Article

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VL - 54

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JO - Chemical Communications

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Surface functional DNA density control by programmable molecular defects

Abstract

ASJC Scopus subject areas

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