6-Cyanouracil derivatives underwent direct substitution reactions with selective primary amines in the presence of N,N-dimethylaminopyridine as a catalyst to give the corresponding 6-alkylaminouracils. This reaction provides a facile access to versatile 6-alkylaminouridine derivatives.
|Number of pages||4|
|Publication status||Published - 2011 Aug 3|
- Nucleophilic aromatic substitution
ASJC Scopus subject areas
- Drug Discovery
- Organic Chemistry