Study of γ-Fe2O3/Au core/shell nanoparticles as the contrast agent for high-Tc SQUID-based low field nuclear magnetic resonance

Kuen Lin Chen, Yao Wei Yeh, Shu Hsien Liao, Chiu Hsien Wu, Li Min Wang

    Research output: Chapter in Book/Report/Conference proceedingConference contribution

    1 Citation (Scopus)

    Abstract

    To improve the image contrast, the so-called contrast agents (CAs) are often used in magnetic resonance image (MRI). CAs are generally paramagnetic or superparamagnetic nanoparticle suspensions. To increase the applicability of low field nuclear magnetic resonance (LFNMR) or LFMRI system, CAs also have been introduced to enhance the image contrast. In this work, we synthesized the γ-Fe2O3/Au core/shell (γ-Fe2O3@Au) nanoparticle and applied it to a homemade high-Tc SQUID-based LFNMR system to study the characteristics of γ-Fe2O3@Au nanoparticle as the contrast agent for the LFNMR system. The average hydrodynamic sizes of the synthesized γ-Fe2O3@Au nanoparticles are 28.38 ± 6.26 nm in diameter. The γ-Fe2O3@Au nanoparticles exhibit a characteristic absorption peak at 536 nm from the contribution of localized surface plasmon resonance of Au shell. The spin-lattice relaxation rate, 1/T1, and the spin-spin relaxation rate, 1/T2, varied with the concentration of γ-Fe2O3@Au nanoparticle. Compared with the data measured in high field (7 Tesla), we found that the γ-Fe2O3@Au nanoparticle is a promising T1-relaxing CA for LFNMR.

    Original languageEnglish
    Title of host publication16th International Conference on Nanotechnology - IEEE NANO 2016
    PublisherInstitute of Electrical and Electronics Engineers Inc.
    Pages585-586
    Number of pages2
    ISBN (Electronic)9781509039142
    DOIs
    Publication statusPublished - 2016 Nov 21
    Event16th IEEE International Conference on Nanotechnology - IEEE NANO 2016 - Sendai, Japan
    Duration: 2016 Aug 222016 Aug 25

    Publication series

    Name16th International Conference on Nanotechnology - IEEE NANO 2016

    Conference

    Conference16th IEEE International Conference on Nanotechnology - IEEE NANO 2016
    CountryJapan
    CitySendai
    Period16/8/2216/8/25

    ASJC Scopus subject areas

    • Electronic, Optical and Magnetic Materials
    • Atomic and Molecular Physics, and Optics

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  • Cite this

    Chen, K. L., Yeh, Y. W., Liao, S. H., Wu, C. H., & Wang, L. M. (2016). Study of γ-Fe2O3/Au core/shell nanoparticles as the contrast agent for high-Tc SQUID-based low field nuclear magnetic resonance. In 16th International Conference on Nanotechnology - IEEE NANO 2016 (pp. 585-586). [7751445] (16th International Conference on Nanotechnology - IEEE NANO 2016). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/NANO.2016.7751445