@inproceedings{5a6bd39f41024875ac5d4d1d072bb2a4,
title = "Single-layer graphene based SPR biochips for tuberculosis bacillus detection",
abstract = "This paper is intended to demonstrate a facile and effective method to construct single layer graphene films onto the self-assembled monolayer (SAM) at Au electrodes based surface plasmon resonance (SPR) biochips integrated loop-mediated isothermal amplification (LAMP) for tuberculosis bacillus (TB) detection. It is a novel Au-SAM-graphene nanocomposites and taking advantages of the striking properties of both graphene and Au film, fundamental understanding in hybrid material manipulation and new electrochemical properties can be obtained. The sensitivity of TB detection in the LAMP-based assay for the amplification of the Insertion Sequence 6110 (IS6110) samples was determined by a single-layer graphene/Au thin film and compared with that of a conventional Au/Cr-based SPR chips. The results show that a graphene/Au SPR offers a potentially powerful assay, with a highly sensitive analysis, that may be applicable as an important tool for bio-marker detection.",
keywords = "Biosensor, Graphene, Insertion Sequence 6110 (IS6110), Loop-mediated isothermal amplification (LAMP), Self-assembled monolayer (SAM), Surface plasmon resonance (SPR), Tuberculosis bacillus (TB)",
author = "Chiu, {Nan Fu} and Huang, {Teng Yi} and Kuo, {Chun Chuan} and Lee, {Wei Che} and Hsieh, {Min Hua} and Lai, {Hsin Chih}",
year = "2012",
doi = "10.1117/12.922698",
language = "English",
isbn = "9780819491190",
series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",
booktitle = "Biophotonics",
note = "Biophotonics: Photonic Solutions for Better Health Care III ; Conference date: 16-04-2012 Through 19-04-2012",
}
