Abstract
A new method for the qualitative and quantitative analysis of citrinin in Monascus by gas-chromatography-selected ion monitoring (SIM) mass spectrometry has been developed. GC separation of citrinin in Monascus extract was achieved without the need for chemical derivatization, and could be detected as a single peak when the SIM mode selected 5 prominent fragmentations (m/z of 220, 205, 177, 105 and 91). The quantitative detection limit for citrinin was ∼1 ppb. Finally, the GC-separated analyte from Monascus extract, at a retention time of 10.89 min, was examined by the method of pattern recognition by comparison with a citrinin standard. The results show that the 2 compounds had a 94% similarity when the SIM mode was used.
Original language | English |
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Pages (from-to) | 283-287 |
Number of pages | 5 |
Journal | Analytical Sciences |
Volume | 18 |
Issue number | 3 |
DOIs | |
Publication status | Published - 2002 |
ASJC Scopus subject areas
- Analytical Chemistry