Silica gel-mediated friedel-crafts reaction of indoles with functionalized nitroallylic acetates via an SN1 process

Ching Yin Ho; Suparna Roy; Yan Ming Chen; Kwunmin Chen

doi:10.1002/jccs.201100643

Silica gel-mediated friedel-crafts reaction of indoles with functionalized nitroallylic acetates via an SN1 process

Ching Yin Ho
, Suparna Roy
, Yan Ming Chen
, Kwunmin Chen^*

^*Corresponding author for this work

Department of Chemistry

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

An environmentally friendly Friedel-Crafts reaction was demonstrated between indoles and functionalized nitroallylic acetates in the presence of silica gel, providing the corresponding C-3-selective regioisomers in good to high overall chemical yields (70-93%).

Original language	English
Pages (from-to)	940-946
Number of pages	7
Journal	Journal of the Chinese Chemical Society
Volume	59
Issue number	8
DOIs	https://doi.org/10.1002/jccs.201100643
Publication status	Published - 2012 Aug

Keywords

Electrophile
Friedel-Crafts reaction
Indole
Nitroallylic acetate
S 1

ASJC Scopus subject areas

General Chemistry

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10.1002/jccs.201100643

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title = "Silica gel-mediated friedel-crafts reaction of indoles with functionalized nitroallylic acetates via an SN1 process",

abstract = "An environmentally friendly Friedel-Crafts reaction was demonstrated between indoles and functionalized nitroallylic acetates in the presence of silica gel, providing the corresponding C-3-selective regioisomers in good to high overall chemical yields (70-93\%).",

keywords = "Electrophile, Friedel-Crafts reaction, Indole, Nitroallylic acetate, S 1",

author = "Ho, \{Ching Yin\} and Suparna Roy and Chen, \{Yan Ming\} and Kwunmin Chen",

year = "2012",

month = aug,

doi = "10.1002/jccs.201100643",

language = "English",

volume = "59",

pages = "940--946",

journal = "Journal of the Chinese Chemical Society",

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publisher = "John Wiley and Sons Inc.",

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TY - JOUR

T1 - Silica gel-mediated friedel-crafts reaction of indoles with functionalized nitroallylic acetates via an SN1 process

AU - Ho, Ching Yin

AU - Roy, Suparna

AU - Chen, Yan Ming

AU - Chen, Kwunmin

PY - 2012/8

Y1 - 2012/8

N2 - An environmentally friendly Friedel-Crafts reaction was demonstrated between indoles and functionalized nitroallylic acetates in the presence of silica gel, providing the corresponding C-3-selective regioisomers in good to high overall chemical yields (70-93%).

AB - An environmentally friendly Friedel-Crafts reaction was demonstrated between indoles and functionalized nitroallylic acetates in the presence of silica gel, providing the corresponding C-3-selective regioisomers in good to high overall chemical yields (70-93%).

KW - Electrophile

KW - Friedel-Crafts reaction

KW - Indole

KW - Nitroallylic acetate

KW - S 1

UR - https://www.scopus.com/pages/publications/84865128261

UR - https://www.scopus.com/pages/publications/84865128261#tab=citedBy

U2 - 10.1002/jccs.201100643

DO - 10.1002/jccs.201100643

M3 - Article

AN - SCOPUS:84865128261

SN - 0009-4536

VL - 59

SP - 940

EP - 946

JO - Journal of the Chinese Chemical Society

JF - Journal of the Chinese Chemical Society

IS - 8

ER -

Silica gel-mediated friedel-crafts reaction of indoles with functionalized nitroallylic acetates via an SN1 process

Abstract

Keywords

ASJC Scopus subject areas

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