Abstract
A rapid method for the synthesis of long-chain fluorinated compounds using a C-C bond-cleavage reaction was developed. Selectfluor was the most effective fluorinating agent of those tested in this study. Long-chain fluoro dioxo nitriles were formed from isoxazoline N-oxides via nitroso intermediates. A Selectfluor-mediated protocol for the synthesis of long-chain fluorinated compounds from cyclohexene-fused isoxazoline N-oxides by using a C-C bond-cleavage reaction is presented.
Original language | English |
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Pages (from-to) | 5743-5749 |
Number of pages | 7 |
Journal | European Journal of Organic Chemistry |
Issue number | 25 |
DOIs | |
Publication status | Published - 2013 Sep 1 |
Keywords
- Cleavage reactions
- Fluorine
- Heterocycles
- Ring opening
- Synthetic methods
ASJC Scopus subject areas
- Physical and Theoretical Chemistry
- Organic Chemistry