Relationship between antidepressant prescription and breast cancer: a population based study in Taiwan

Vincent Chin Hung Chen; Yin To Liao; Dah Cherng Yeh; Hsien Chun Tseng; Robert Stewart; Charles Tzu Chi Lee

doi:10.1002/pon.3929

Relationship between antidepressant prescription and breast cancer: a population based study in Taiwan

Vincent Chin Hung Chen, Yin To Liao, Dah Cherng Yeh, Hsien Chun Tseng, Robert Stewart, Charles Tzu Chi Lee^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

10 Citations (Scopus)

Abstract

Objective: To investigate the association between antidepressant prescription and breast cancer. Methods: The National Health Research Institute in Taiwan provided a database of 1 000 000 random subjects for this study. We identified 14 737 new antidepressant female users who were more than 15 years old during 1999–2005 with at least 10 prescriptions and one year exposure to an antidepressant. These were matched 1:1 by age and residence to non-antidepressant users from the same database to compare the risk of breast cancer. Results: In a model adjusted by age, residence, insurance amount, and depressive disorder, antidepressant prescription was not associated with breast cancer risk. This held true for both selective serotonin re-uptake inhibitors (SSRIs) and tricyclic antidepressants. Conclusions: There was no evidence for an association between antidepressant prescription and the risk of breast cancer.

Original language	English
Pages (from-to)	803-807
Number of pages	5
Journal	Psycho-Oncology
DOIs	https://doi.org/10.1002/pon.3929
Publication status	Published - 2016 Jul 1
Externally published	Yes

ASJC Scopus subject areas

Experimental and Cognitive Psychology
Oncology
Psychiatry and Mental health

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1002/pon.3929

Cite this

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title = "Relationship between antidepressant prescription and breast cancer: a population based study in Taiwan",

abstract = "Objective: To investigate the association between antidepressant prescription and breast cancer. Methods: The National Health Research Institute in Taiwan provided a database of 1 000 000 random subjects for this study. We identified 14 737 new antidepressant female users who were more than 15 years old during 1999–2005 with at least 10 prescriptions and one year exposure to an antidepressant. These were matched 1:1 by age and residence to non-antidepressant users from the same database to compare the risk of breast cancer. Results: In a model adjusted by age, residence, insurance amount, and depressive disorder, antidepressant prescription was not associated with breast cancer risk. This held true for both selective serotonin re-uptake inhibitors (SSRIs) and tricyclic antidepressants. Conclusions: There was no evidence for an association between antidepressant prescription and the risk of breast cancer.",

author = "Chen, {Vincent Chin Hung} and Liao, {Yin To} and Yeh, {Dah Cherng} and Tseng, {Hsien Chun} and Robert Stewart and Lee, {Charles Tzu Chi}",

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doi = "10.1002/pon.3929",

language = "English",

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T1 - Relationship between antidepressant prescription and breast cancer

T2 - a population based study in Taiwan

AU - Chen, Vincent Chin Hung

AU - Liao, Yin To

AU - Yeh, Dah Cherng

AU - Tseng, Hsien Chun

AU - Stewart, Robert

AU - Lee, Charles Tzu Chi

PY - 2016/7/1

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N2 - Objective: To investigate the association between antidepressant prescription and breast cancer. Methods: The National Health Research Institute in Taiwan provided a database of 1 000 000 random subjects for this study. We identified 14 737 new antidepressant female users who were more than 15 years old during 1999–2005 with at least 10 prescriptions and one year exposure to an antidepressant. These were matched 1:1 by age and residence to non-antidepressant users from the same database to compare the risk of breast cancer. Results: In a model adjusted by age, residence, insurance amount, and depressive disorder, antidepressant prescription was not associated with breast cancer risk. This held true for both selective serotonin re-uptake inhibitors (SSRIs) and tricyclic antidepressants. Conclusions: There was no evidence for an association between antidepressant prescription and the risk of breast cancer.

AB - Objective: To investigate the association between antidepressant prescription and breast cancer. Methods: The National Health Research Institute in Taiwan provided a database of 1 000 000 random subjects for this study. We identified 14 737 new antidepressant female users who were more than 15 years old during 1999–2005 with at least 10 prescriptions and one year exposure to an antidepressant. These were matched 1:1 by age and residence to non-antidepressant users from the same database to compare the risk of breast cancer. Results: In a model adjusted by age, residence, insurance amount, and depressive disorder, antidepressant prescription was not associated with breast cancer risk. This held true for both selective serotonin re-uptake inhibitors (SSRIs) and tricyclic antidepressants. Conclusions: There was no evidence for an association between antidepressant prescription and the risk of breast cancer.

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Relationship between antidepressant prescription and breast cancer: a population based study in Taiwan

Abstract

ASJC Scopus subject areas

UN SDGs

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