Recent topics of phosphine-mediated reactions

Praneeth Karanam, Ganapuram Madhusudhan Reddy, Srinivasa Rao Koppolu, Wenwei Lin*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

49 Citations (Scopus)


Phosphines constitute key organophosphorus reagents that are being widely used in industry as well as in research laboratories since over a century. Specifically, in last two decades, there have been numerous reports on phosphine-mediated and phosphine-catalyzed reactions. In terms of industrial application, phosphine-mediated reactions have received much attention when compared to the catalytic versions for the synthesis of a variety of structurally diverse organic frameworks. In this digest review, we wish to summarize the recent advances (2014–2017) in phosphine-mediated reactions that are primarily based on stoichiometric application of phosphine.

Original languageEnglish
Pages (from-to)59-76
Number of pages18
JournalTetrahedron Letters
Issue number2
Publication statusPublished - 2018 Jan 10


  • Annulations
  • Huisgen zwitterions
  • Kukhtin-Ramirez adducts
  • Phosphine-mediated reactions
  • Wittig reactions

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry


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