Reactions of β-nitrostyrenes with stabilized nucleophiles

Ching Fa Yao*, Cherng Shi Yang, Hui Yu Fang

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

12 Citations (Scopus)


β-Nitrostyrenes 1 react with stabilized nucleophiles to generate hydroximoyl chloride 2 after workup with ice cold concentrated hydrochloric acid. One-pot synthesis of five-membered carbocycles or cyclic ethers from the Michael addition of the carbon nucleophiles or alkoxides to the β-nitrostyrenes is reported.

Original languageEnglish
Pages (from-to)6419-6420
Number of pages2
JournalTetrahedron Letters
Issue number36
Publication statusPublished - 1997 Sept 8

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry


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