Preparation of tetrasubstituted furans via intramolecular wittig reactions with phosphorus ylides as intermediates

Tzu Ting Kao; Siang En Syu; Yi Wun Jhang; Wenwei Lin

doi:10.1021/ol101080q

Preparation of tetrasubstituted furans via intramolecular wittig reactions with phosphorus ylides as intermediates

Tzu Ting Kao, Siang En Syu, Yi Wun Jhang, Wenwei Lin

Department of Chemistry

Research output: Contribution to journal › Article › peer-review

88 Citations (Scopus)

Abstract

Novel preparation of tetrasubstituted furans, starting from the Michael acceptors, tributylphosphine, and acyl chlorides, is realized. A broad range of highly functional furans can be efficiently generated in one step at room temperature within 10 min to 21 h in moderate to high yields (60-99%). The reaction was proposed to proceed via intramolecular Wittig-type reactions, using phosphorus ylides as intermediates.

Original language	English
Pages (from-to)	3066-3069
Number of pages	4
Journal	Organic Letters
Volume	12
Issue number	13
DOIs	https://doi.org/10.1021/ol101080q
Publication status	Published - 2010 Jul 2

ASJC Scopus subject areas

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

Access to Document

10.1021/ol101080q

Fingerprint Dive into the research topics of 'Preparation of tetrasubstituted furans via intramolecular wittig reactions with phosphorus ylides as intermediates'. Together they form a unique fingerprint.

Cite this

@article{1957c0cdfb6d46168a46f1aa90c26021,

title = "Preparation of tetrasubstituted furans via intramolecular wittig reactions with phosphorus ylides as intermediates",

abstract = "Novel preparation of tetrasubstituted furans, starting from the Michael acceptors, tributylphosphine, and acyl chlorides, is realized. A broad range of highly functional furans can be efficiently generated in one step at room temperature within 10 min to 21 h in moderate to high yields (60-99%). The reaction was proposed to proceed via intramolecular Wittig-type reactions, using phosphorus ylides as intermediates.",

author = "Kao, {Tzu Ting} and Syu, {Siang En} and Jhang, {Yi Wun} and Wenwei Lin",

year = "2010",

month = jul,

day = "2",

doi = "10.1021/ol101080q",

language = "English",

volume = "12",

pages = "3066--3069",

journal = "Organic Letters",

issn = "1523-7060",

publisher = "American Chemical Society",

number = "13",

}

TY - JOUR

T1 - Preparation of tetrasubstituted furans via intramolecular wittig reactions with phosphorus ylides as intermediates

AU - Kao, Tzu Ting

AU - Syu, Siang En

AU - Jhang, Yi Wun

AU - Lin, Wenwei

PY - 2010/7/2

Y1 - 2010/7/2

N2 - Novel preparation of tetrasubstituted furans, starting from the Michael acceptors, tributylphosphine, and acyl chlorides, is realized. A broad range of highly functional furans can be efficiently generated in one step at room temperature within 10 min to 21 h in moderate to high yields (60-99%). The reaction was proposed to proceed via intramolecular Wittig-type reactions, using phosphorus ylides as intermediates.

AB - Novel preparation of tetrasubstituted furans, starting from the Michael acceptors, tributylphosphine, and acyl chlorides, is realized. A broad range of highly functional furans can be efficiently generated in one step at room temperature within 10 min to 21 h in moderate to high yields (60-99%). The reaction was proposed to proceed via intramolecular Wittig-type reactions, using phosphorus ylides as intermediates.

UR - http://www.scopus.com/inward/record.url?scp=77954097756&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77954097756&partnerID=8YFLogxK

U2 - 10.1021/ol101080q

DO - 10.1021/ol101080q

M3 - Article

C2 - 20521775

AN - SCOPUS:77954097756

VL - 12

SP - 3066

EP - 3069

JO - Organic Letters

JF - Organic Letters

SN - 1523-7060

IS - 13

ER -

Preparation of tetrasubstituted furans via intramolecular wittig reactions with phosphorus ylides as intermediates

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Cite this