Abstract
Novel preparation of tetrasubstituted furans, starting from the Michael acceptors, tributylphosphine, and acyl chlorides, is realized. A broad range of highly functional furans can be efficiently generated in one step at room temperature within 10 min to 21 h in moderate to high yields (60-99%). The reaction was proposed to proceed via intramolecular Wittig-type reactions, using phosphorus ylides as intermediates.
| Original language | English |
|---|---|
| Pages (from-to) | 3066-3069 |
| Number of pages | 4 |
| Journal | Organic Letters |
| Volume | 12 |
| Issue number | 13 |
| DOIs | |
| Publication status | Published - 2010 Jul 2 |
ASJC Scopus subject areas
- Biochemistry
- Physical and Theoretical Chemistry
- Organic Chemistry
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Kao, T. T., Syu, S. E., Jhang, Y. W., & Lin, W. (2010). Preparation of tetrasubstituted furans via intramolecular wittig reactions with phosphorus ylides as intermediates. Organic Letters, 12(13), 3066-3069. https://doi.org/10.1021/ol101080q