Abstract
Novel preparation of tetrasubstituted furans, starting from the Michael acceptors, tributylphosphine, and acyl chlorides, is realized. A broad range of highly functional furans can be efficiently generated in one step at room temperature within 10 min to 21 h in moderate to high yields (60-99%). The reaction was proposed to proceed via intramolecular Wittig-type reactions, using phosphorus ylides as intermediates.
| Original language | English |
|---|---|
| Pages (from-to) | 3066-3069 |
| Number of pages | 4 |
| Journal | Organic Letters |
| Volume | 12 |
| Issue number | 13 |
| DOIs | |
| Publication status | Published - 2010 Jul 2 |
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ASJC Scopus subject areas
- Biochemistry
- Physical and Theoretical Chemistry
- Organic Chemistry
Cite this
Preparation of tetrasubstituted furans via intramolecular wittig reactions with phosphorus ylides as intermediates. / Kao, Tzu Ting; Syu, Siang En; Jhang, Yi Wun; Lin, Wenwei.
In: Organic Letters, Vol. 12, No. 13, 02.07.2010, p. 3066-3069.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Preparation of tetrasubstituted furans via intramolecular wittig reactions with phosphorus ylides as intermediates
AU - Kao, Tzu Ting
AU - Syu, Siang En
AU - Jhang, Yi Wun
AU - Lin, Wenwei
PY - 2010/7/2
Y1 - 2010/7/2
N2 - Novel preparation of tetrasubstituted furans, starting from the Michael acceptors, tributylphosphine, and acyl chlorides, is realized. A broad range of highly functional furans can be efficiently generated in one step at room temperature within 10 min to 21 h in moderate to high yields (60-99%). The reaction was proposed to proceed via intramolecular Wittig-type reactions, using phosphorus ylides as intermediates.
AB - Novel preparation of tetrasubstituted furans, starting from the Michael acceptors, tributylphosphine, and acyl chlorides, is realized. A broad range of highly functional furans can be efficiently generated in one step at room temperature within 10 min to 21 h in moderate to high yields (60-99%). The reaction was proposed to proceed via intramolecular Wittig-type reactions, using phosphorus ylides as intermediates.
UR - http://www.scopus.com/inward/record.url?scp=77954097756&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=77954097756&partnerID=8YFLogxK
U2 - 10.1021/ol101080q
DO - 10.1021/ol101080q
M3 - Article
C2 - 20521775
AN - SCOPUS:77954097756
VL - 12
SP - 3066
EP - 3069
JO - Organic Letters
JF - Organic Letters
SN - 1523-7060
IS - 13
ER -