Preparation of functional phosphorus zwitterions from activated alkanes, aldehydes, and tributylphosphine: Synthesis of polysubstituted furo[3,2-c ]coumarins

Chia Jui Lee; Yeong Jiunn Jang; Zong Ze Wu; Wenwei Lin

doi:10.1021/ol3005479

Preparation of functional phosphorus zwitterions from activated alkanes, aldehydes, and tributylphosphine: Synthesis of polysubstituted furo[3,2-c ]coumarins

Chia Jui Lee, Yeong Jiunn Jang, Zong Ze Wu, Wenwei Lin

Department of Chemistry

Research output: Contribution to journal › Article › peer-review

51 Citations (Scopus)

Abstract

A general preparation of new types of highly functional phosphorus zwitterions is realized via tandem three-component reactions using the corresponding functional alkanes, aldehydes, and Bu ₃P. Starting from our novel zwitterions as synthetic reagents with commercially available acid chlorides in a one-step procedure provides an attractive approach toward furo[3,2-c]coumarins.

Original language	English
Pages (from-to)	1906-1909
Number of pages	4
Journal	Organic Letters
Volume	14
Issue number	7
DOIs	https://doi.org/10.1021/ol3005479
Publication status	Published - 2012 Apr 6

ASJC Scopus subject areas

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

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abstract = "A general preparation of new types of highly functional phosphorus zwitterions is realized via tandem three-component reactions using the corresponding functional alkanes, aldehydes, and Bu 3P. Starting from our novel zwitterions as synthetic reagents with commercially available acid chlorides in a one-step procedure provides an attractive approach toward furo[3,2-c]coumarins.",

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AU - Wu, Zong Ze

AU - Lin, Wenwei

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AB - A general preparation of new types of highly functional phosphorus zwitterions is realized via tandem three-component reactions using the corresponding functional alkanes, aldehydes, and Bu 3P. Starting from our novel zwitterions as synthetic reagents with commercially available acid chlorides in a one-step procedure provides an attractive approach toward furo[3,2-c]coumarins.

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