Preparation of functional phosphorus zwitterions from activated alkanes, aldehydes, and tributylphosphine: Synthesis of polysubstituted furo[3,2-c ]coumarins

Chia Jui Lee; Yeong Jiunn Jang; Zong Ze Wu; Wenwei Lin

doi:10.1021/ol3005479

Preparation of functional phosphorus zwitterions from activated alkanes, aldehydes, and tributylphosphine: Synthesis of polysubstituted furo[3,2-c ]coumarins

Chia Jui Lee, Yeong Jiunn Jang, Zong Ze Wu, Wenwei Lin

Department of Chemistry

Research output: Contribution to journal › Article

48 Citations (Scopus)

Abstract

A general preparation of new types of highly functional phosphorus zwitterions is realized via tandem three-component reactions using the corresponding functional alkanes, aldehydes, and Bu ₃P. Starting from our novel zwitterions as synthetic reagents with commercially available acid chlorides in a one-step procedure provides an attractive approach toward furo[3,2-c]coumarins.

Original language	English
Pages (from-to)	1906-1909
Number of pages	4
Journal	Organic Letters
Volume	14
Issue number	7
DOIs	https://doi.org/10.1021/ol3005479
Publication status	Published - 2012 Apr 6

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ASJC Scopus subject areas

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

Cite this

Lee, C. J., Jang, Y. J., Wu, Z. Z., & Lin, W. (2012). Preparation of functional phosphorus zwitterions from activated alkanes, aldehydes, and tributylphosphine: Synthesis of polysubstituted furo[3,2-c ]coumarins. Organic Letters, 14(7), 1906-1909. https://doi.org/10.1021/ol3005479

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Access to Document

10.1021/ol3005479