Preparation of functional phosphorus zwitterions from activated alkanes, aldehydes, and tributylphosphine: Synthesis of polysubstituted furo[3,2-c ]coumarins

Chia Jui Lee, Yeong Jiunn Jang, Zong Ze Wu, Wenwei Lin

Research output: Contribution to journalArticle

48 Citations (Scopus)


A general preparation of new types of highly functional phosphorus zwitterions is realized via tandem three-component reactions using the corresponding functional alkanes, aldehydes, and Bu 3P. Starting from our novel zwitterions as synthetic reagents with commercially available acid chlorides in a one-step procedure provides an attractive approach toward furo[3,2-c]coumarins.

Original languageEnglish
Pages (from-to)1906-1909
Number of pages4
JournalOrganic Letters
Issue number7
Publication statusPublished - 2012 Apr 6


ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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