Preparation of functional benzofurans and indoles via chemoselective intramolecular Wittig reactions

Yu Ting Lee, Yeong Jiunn Jang, Siang En Syu, Shu Chi Chou, Chia Jui Lee, Wenwei Lin

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

A general preparation of new types of benzofurans, benzothiophenes and indoles is realized via chemoselective intramolecular Wittig reactions with the corresponding ester, thioester and amide functionalities using in situ formed phosphorus ylides as key intermediates. The reaction conditions are very mild, and numerous Michael acceptors and commercially available acid chlorides can be applied very efficiently in a one-step procedure.

Original languageEnglish
Pages (from-to)8135-8137
Number of pages3
JournalChemical Communications
Volume48
Issue number65
DOIs
Publication statusPublished - 2012 Aug 21

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Benzofurans
Indoles
Amides
Phosphorus
Chlorides
Esters
Acids
benzothiophene

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

Cite this

Preparation of functional benzofurans and indoles via chemoselective intramolecular Wittig reactions. / Lee, Yu Ting; Jang, Yeong Jiunn; Syu, Siang En; Chou, Shu Chi; Lee, Chia Jui; Lin, Wenwei.

In: Chemical Communications, Vol. 48, No. 65, 21.08.2012, p. 8135-8137.

Research output: Contribution to journalArticle

Lee, Yu Ting ; Jang, Yeong Jiunn ; Syu, Siang En ; Chou, Shu Chi ; Lee, Chia Jui ; Lin, Wenwei. / Preparation of functional benzofurans and indoles via chemoselective intramolecular Wittig reactions. In: Chemical Communications. 2012 ; Vol. 48, No. 65. pp. 8135-8137.
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