Preparation of electrospun alginate fibers with chitosan sheath

Jung Jhih Chang, Yen Hsien Lee, Meng Hsiu Wu, Ming Chien Yang, Chiang-Ting Chien

Research output: Contribution to journalArticle

38 Citations (Scopus)

Abstract

In this study, alginate (AL) fibers were electrospun and coagulated with chitosan (ChS) and ethanol using a single spinneret. These fibers exhibited a core-sheath structure that was revealed using a confocal laser scanning microscope (CLSM) and fluorescence-labeled polymers. The resulting fibers were examined using a field emission scanning electron microscope (FESEM) for the fiber size and morphology. The average diameter of the fibers ranged from 600 to 900 nm depending on the electrospinning parameters. To mimic the stability of alginate fibers in physiological fluids, the release of alginate from these fibers in normal saline was also tested. The results demonstrated that the core-sheath structure of alginate fiber can greatly reduce the degradation by 40% for 3 d in physiological environment.

Original languageEnglish
Pages (from-to)2357-2361
Number of pages5
JournalCarbohydrate Polymers
Volume87
Issue number3
DOIs
Publication statusPublished - 2012 Feb 14

Fingerprint

Alginate
Chitosan
Fibers
Scanning
alginic acid
Electrospinning
Field emission
Polymers
Microscopes
Ethanol
Electron microscopes
Fluorescence
Degradation
Fluids
Lasers

Keywords

  • Chitosan
  • Core-sheath structure
  • Electrospinning
  • Fluorescent labeling
  • Sodium alginate

ASJC Scopus subject areas

  • Organic Chemistry
  • Polymers and Plastics
  • Materials Chemistry

Cite this

Preparation of electrospun alginate fibers with chitosan sheath. / Chang, Jung Jhih; Lee, Yen Hsien; Wu, Meng Hsiu; Yang, Ming Chien; Chien, Chiang-Ting.

In: Carbohydrate Polymers, Vol. 87, No. 3, 14.02.2012, p. 2357-2361.

Research output: Contribution to journalArticle

Chang, Jung Jhih ; Lee, Yen Hsien ; Wu, Meng Hsiu ; Yang, Ming Chien ; Chien, Chiang-Ting. / Preparation of electrospun alginate fibers with chitosan sheath. In: Carbohydrate Polymers. 2012 ; Vol. 87, No. 3. pp. 2357-2361.
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