Practical synthesis of N -substituted cyanamides via tiemann rearrangement of amidoximes

  • Chia Chi Lin
  • , Tsung Han Hsieh
  • , Pen Yuan Liao
  • , Zhen Yuan Liao
  • , Chih Wei Chang
  • , Yu Chiao Shih
  • , Wen Hsiung Yeh
  • , Tun Cheng Chien*
  • *Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

67 Citations (Scopus)

Abstract

A facile and general synthesis of various N-substituted cyanamides was accomplished by the Tiemann rearrangement of amidoximes with benzenesulfonyl chlorides (TsCl or o-NsCl) and DIPEA.

Original languageEnglish
Pages (from-to)892-895
Number of pages4
JournalOrganic Letters
Volume16
Issue number3
DOIs
Publication statusPublished - 2014 Feb 7

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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