Performance of white organic light-emitting diode for portable optical biosensor

Briliant Adhi Prabowo; Li Chen Su; Ying Feng Chang; Hsin Chih Lai; Nan Fu Chiu; Kou Chen Liu

doi:10.1016/j.snb.2015.09.059

Performance of white organic light-emitting diode for portable optical biosensor

Briliant Adhi Prabowo, Li Chen Su, Ying Feng Chang, Hsin Chih Lai^*, Nan Fu Chiu, Kou Chen Liu

^*Corresponding author for this work

Undergraduate Program of Electro-Optical Engineering

Research output: Contribution to journal › Article › peer-review

26 Citations (Scopus)

Abstract

A white organic light-emitting diode (OLED) with enhanced sensitivity has been demonstrated as a novel light source in a portable surface plasmon resonance (SPR) optical biosensor. A disposable broad-spectral OLED was employed on the leg side of isosceles trapezoid prism for a fixed angle of incident light. Bimetallic Ag/Au composition layers were used as sensing layers and their structures evaluated such that the wavelength resonance occurred at the peak of the light spectrum. The SPR signal detection applied differential intensities at two reference wavelengths. We show that the integration of a white spectral OLED on an SPR sensor improved the sensor's sensitivity by ∼19.29% compared to an SPR sensor system using a green OLED for a bimetallic Ag/Au sensing layer. The limit of detection (LOD) of 2.4 × 10^-6 refractive index units (RIU) has been established in the range of refractive index samples (Δn) around 3.6 × 10^-3 RIU. This optical sensor demonstrated the capability of rapid, real-time monitoring operation. The activation of self-assembled monolayer (SAM), antibody immobilization, and biomolecular interaction detection of immunoglobulin G (IgG) protein are recorded successfully with a detection limit around 40.3 pg/mL.

Original language	English
Pages (from-to)	1058-1065
Number of pages	8
Journal	Sensors and Actuators, B: Chemical
Volume	222
DOIs	https://doi.org/10.1016/j.snb.2015.09.059
Publication status	Published - 2016 Jan 1

Keywords

Biosensor
OLED
Portable
Surface plasmon resonance
White light

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Instrumentation
Condensed Matter Physics
Surfaces, Coatings and Films
Metals and Alloys
Electrical and Electronic Engineering
Materials Chemistry

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10.1016/j.snb.2015.09.059

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title = "Performance of white organic light-emitting diode for portable optical biosensor",

abstract = "A white organic light-emitting diode (OLED) with enhanced sensitivity has been demonstrated as a novel light source in a portable surface plasmon resonance (SPR) optical biosensor. A disposable broad-spectral OLED was employed on the leg side of isosceles trapezoid prism for a fixed angle of incident light. Bimetallic Ag/Au composition layers were used as sensing layers and their structures evaluated such that the wavelength resonance occurred at the peak of the light spectrum. The SPR signal detection applied differential intensities at two reference wavelengths. We show that the integration of a white spectral OLED on an SPR sensor improved the sensor's sensitivity by ∼19.29% compared to an SPR sensor system using a green OLED for a bimetallic Ag/Au sensing layer. The limit of detection (LOD) of 2.4 × 10-6 refractive index units (RIU) has been established in the range of refractive index samples (Δn) around 3.6 × 10-3 RIU. This optical sensor demonstrated the capability of rapid, real-time monitoring operation. The activation of self-assembled monolayer (SAM), antibody immobilization, and biomolecular interaction detection of immunoglobulin G (IgG) protein are recorded successfully with a detection limit around 40.3 pg/mL.",

keywords = "Biosensor, OLED, Portable, Surface plasmon resonance, White light",

author = "Prabowo, {Briliant Adhi} and Su, {Li Chen} and Chang, {Ying Feng} and Lai, {Hsin Chih} and Chiu, {Nan Fu} and Liu, {Kou Chen}",

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AU - Prabowo, Briliant Adhi

AU - Su, Li Chen

AU - Chang, Ying Feng

AU - Lai, Hsin Chih

AU - Chiu, Nan Fu

AU - Liu, Kou Chen

PY - 2016/1/1

Y1 - 2016/1/1

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AB - A white organic light-emitting diode (OLED) with enhanced sensitivity has been demonstrated as a novel light source in a portable surface plasmon resonance (SPR) optical biosensor. A disposable broad-spectral OLED was employed on the leg side of isosceles trapezoid prism for a fixed angle of incident light. Bimetallic Ag/Au composition layers were used as sensing layers and their structures evaluated such that the wavelength resonance occurred at the peak of the light spectrum. The SPR signal detection applied differential intensities at two reference wavelengths. We show that the integration of a white spectral OLED on an SPR sensor improved the sensor's sensitivity by ∼19.29% compared to an SPR sensor system using a green OLED for a bimetallic Ag/Au sensing layer. The limit of detection (LOD) of 2.4 × 10-6 refractive index units (RIU) has been established in the range of refractive index samples (Δn) around 3.6 × 10-3 RIU. This optical sensor demonstrated the capability of rapid, real-time monitoring operation. The activation of self-assembled monolayer (SAM), antibody immobilization, and biomolecular interaction detection of immunoglobulin G (IgG) protein are recorded successfully with a detection limit around 40.3 pg/mL.

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KW - Portable

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KW - White light

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Performance of white organic light-emitting diode for portable optical biosensor

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Keywords

ASJC Scopus subject areas

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