Performance of white organic light-emitting diode for portable optical biosensor

Briliant Adhi Prabowo, Li Chen Su, Ying Feng Chang, Hsin Chih Lai, Nan Fu Chiu, Kou Chen Liu

Research output: Contribution to journalArticle

10 Citations (Scopus)

Abstract

A white organic light-emitting diode (OLED) with enhanced sensitivity has been demonstrated as a novel light source in a portable surface plasmon resonance (SPR) optical biosensor. A disposable broad-spectral OLED was employed on the leg side of isosceles trapezoid prism for a fixed angle of incident light. Bimetallic Ag/Au composition layers were used as sensing layers and their structures evaluated such that the wavelength resonance occurred at the peak of the light spectrum. The SPR signal detection applied differential intensities at two reference wavelengths. We show that the integration of a white spectral OLED on an SPR sensor improved the sensor's sensitivity by ∼19.29% compared to an SPR sensor system using a green OLED for a bimetallic Ag/Au sensing layer. The limit of detection (LOD) of 2.4 × 10-6 refractive index units (RIU) has been established in the range of refractive index samples (Δn) around 3.6 × 10-3 RIU. This optical sensor demonstrated the capability of rapid, real-time monitoring operation. The activation of self-assembled monolayer (SAM), antibody immobilization, and biomolecular interaction detection of immunoglobulin G (IgG) protein are recorded successfully with a detection limit around 40.3 pg/mL.

Original languageEnglish
Pages (from-to)1058-1065
Number of pages8
JournalSensors and Actuators, B: Chemical
Volume222
DOIs
Publication statusPublished - 2016 Jan 1

Fingerprint

Organic light emitting diodes (OLED)
Surface plasmon resonance
bioinstrumentation
Biosensors
light emitting diodes
surface plasmon resonance
Refractive index
refractivity
Sensors
sensors
Wavelength
Signal detection
trapezoids
Optical sensors
Self assembled monolayers
Prisms
GTP-Binding Proteins
Antibodies
signal detection
Light sources

Keywords

  • Biosensor
  • OLED
  • Portable
  • Surface plasmon resonance
  • White light

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Instrumentation
  • Condensed Matter Physics
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Electrical and Electronic Engineering
  • Materials Chemistry

Cite this

Performance of white organic light-emitting diode for portable optical biosensor. / Prabowo, Briliant Adhi; Su, Li Chen; Chang, Ying Feng; Lai, Hsin Chih; Chiu, Nan Fu; Liu, Kou Chen.

In: Sensors and Actuators, B: Chemical, Vol. 222, 01.01.2016, p. 1058-1065.

Research output: Contribution to journalArticle

Prabowo, Briliant Adhi ; Su, Li Chen ; Chang, Ying Feng ; Lai, Hsin Chih ; Chiu, Nan Fu ; Liu, Kou Chen. / Performance of white organic light-emitting diode for portable optical biosensor. In: Sensors and Actuators, B: Chemical. 2016 ; Vol. 222. pp. 1058-1065.
@article{842c4bd9f2f540469aa1bd7a9df9a5fe,
title = "Performance of white organic light-emitting diode for portable optical biosensor",
abstract = "A white organic light-emitting diode (OLED) with enhanced sensitivity has been demonstrated as a novel light source in a portable surface plasmon resonance (SPR) optical biosensor. A disposable broad-spectral OLED was employed on the leg side of isosceles trapezoid prism for a fixed angle of incident light. Bimetallic Ag/Au composition layers were used as sensing layers and their structures evaluated such that the wavelength resonance occurred at the peak of the light spectrum. The SPR signal detection applied differential intensities at two reference wavelengths. We show that the integration of a white spectral OLED on an SPR sensor improved the sensor's sensitivity by ∼19.29{\%} compared to an SPR sensor system using a green OLED for a bimetallic Ag/Au sensing layer. The limit of detection (LOD) of 2.4 × 10-6 refractive index units (RIU) has been established in the range of refractive index samples (Δn) around 3.6 × 10-3 RIU. This optical sensor demonstrated the capability of rapid, real-time monitoring operation. The activation of self-assembled monolayer (SAM), antibody immobilization, and biomolecular interaction detection of immunoglobulin G (IgG) protein are recorded successfully with a detection limit around 40.3 pg/mL.",
keywords = "Biosensor, OLED, Portable, Surface plasmon resonance, White light",
author = "Prabowo, {Briliant Adhi} and Su, {Li Chen} and Chang, {Ying Feng} and Lai, {Hsin Chih} and Chiu, {Nan Fu} and Liu, {Kou Chen}",
year = "2016",
month = "1",
day = "1",
doi = "10.1016/j.snb.2015.09.059",
language = "English",
volume = "222",
pages = "1058--1065",
journal = "Sensors and Actuators, B: Chemical",
issn = "0925-4005",
publisher = "Elsevier",

}

TY - JOUR

T1 - Performance of white organic light-emitting diode for portable optical biosensor

AU - Prabowo, Briliant Adhi

AU - Su, Li Chen

AU - Chang, Ying Feng

AU - Lai, Hsin Chih

AU - Chiu, Nan Fu

AU - Liu, Kou Chen

PY - 2016/1/1

Y1 - 2016/1/1

N2 - A white organic light-emitting diode (OLED) with enhanced sensitivity has been demonstrated as a novel light source in a portable surface plasmon resonance (SPR) optical biosensor. A disposable broad-spectral OLED was employed on the leg side of isosceles trapezoid prism for a fixed angle of incident light. Bimetallic Ag/Au composition layers were used as sensing layers and their structures evaluated such that the wavelength resonance occurred at the peak of the light spectrum. The SPR signal detection applied differential intensities at two reference wavelengths. We show that the integration of a white spectral OLED on an SPR sensor improved the sensor's sensitivity by ∼19.29% compared to an SPR sensor system using a green OLED for a bimetallic Ag/Au sensing layer. The limit of detection (LOD) of 2.4 × 10-6 refractive index units (RIU) has been established in the range of refractive index samples (Δn) around 3.6 × 10-3 RIU. This optical sensor demonstrated the capability of rapid, real-time monitoring operation. The activation of self-assembled monolayer (SAM), antibody immobilization, and biomolecular interaction detection of immunoglobulin G (IgG) protein are recorded successfully with a detection limit around 40.3 pg/mL.

AB - A white organic light-emitting diode (OLED) with enhanced sensitivity has been demonstrated as a novel light source in a portable surface plasmon resonance (SPR) optical biosensor. A disposable broad-spectral OLED was employed on the leg side of isosceles trapezoid prism for a fixed angle of incident light. Bimetallic Ag/Au composition layers were used as sensing layers and their structures evaluated such that the wavelength resonance occurred at the peak of the light spectrum. The SPR signal detection applied differential intensities at two reference wavelengths. We show that the integration of a white spectral OLED on an SPR sensor improved the sensor's sensitivity by ∼19.29% compared to an SPR sensor system using a green OLED for a bimetallic Ag/Au sensing layer. The limit of detection (LOD) of 2.4 × 10-6 refractive index units (RIU) has been established in the range of refractive index samples (Δn) around 3.6 × 10-3 RIU. This optical sensor demonstrated the capability of rapid, real-time monitoring operation. The activation of self-assembled monolayer (SAM), antibody immobilization, and biomolecular interaction detection of immunoglobulin G (IgG) protein are recorded successfully with a detection limit around 40.3 pg/mL.

KW - Biosensor

KW - OLED

KW - Portable

KW - Surface plasmon resonance

KW - White light

UR - http://www.scopus.com/inward/record.url?scp=84942902570&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84942902570&partnerID=8YFLogxK

U2 - 10.1016/j.snb.2015.09.059

DO - 10.1016/j.snb.2015.09.059

M3 - Article

AN - SCOPUS:84942902570

VL - 222

SP - 1058

EP - 1065

JO - Sensors and Actuators, B: Chemical

JF - Sensors and Actuators, B: Chemical

SN - 0925-4005

ER -