Performance of white organic light-emitting diode for portable optical biosensor

Briliant Adhi Prabowo, Li Chen Su, Ying Feng Chang, Hsin Chih Lai, Nan Fu Chiu, Kou Chen Liu

    Research output: Contribution to journalArticlepeer-review

    18 Citations (Scopus)

    Abstract

    A white organic light-emitting diode (OLED) with enhanced sensitivity has been demonstrated as a novel light source in a portable surface plasmon resonance (SPR) optical biosensor. A disposable broad-spectral OLED was employed on the leg side of isosceles trapezoid prism for a fixed angle of incident light. Bimetallic Ag/Au composition layers were used as sensing layers and their structures evaluated such that the wavelength resonance occurred at the peak of the light spectrum. The SPR signal detection applied differential intensities at two reference wavelengths. We show that the integration of a white spectral OLED on an SPR sensor improved the sensor's sensitivity by ∼19.29% compared to an SPR sensor system using a green OLED for a bimetallic Ag/Au sensing layer. The limit of detection (LOD) of 2.4 × 10-6 refractive index units (RIU) has been established in the range of refractive index samples (Δn) around 3.6 × 10-3 RIU. This optical sensor demonstrated the capability of rapid, real-time monitoring operation. The activation of self-assembled monolayer (SAM), antibody immobilization, and biomolecular interaction detection of immunoglobulin G (IgG) protein are recorded successfully with a detection limit around 40.3 pg/mL.

    Original languageEnglish
    Pages (from-to)1058-1065
    Number of pages8
    JournalSensors and Actuators, B: Chemical
    Volume222
    DOIs
    Publication statusPublished - 2016 Jan 1

    Keywords

    • Biosensor
    • OLED
    • Portable
    • Surface plasmon resonance
    • White light

    ASJC Scopus subject areas

    • Electronic, Optical and Magnetic Materials
    • Instrumentation
    • Condensed Matter Physics
    • Surfaces, Coatings and Films
    • Metals and Alloys
    • Electrical and Electronic Engineering
    • Materials Chemistry

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