Abstract
A highly chemoselective PPh3-catalyzed three-component reaction of an imine, alkyl vinyl ketone, and phthalimide or succinimide is developed. Various highly functional adducts with high diastereoselectivities can be generated via aza-Morita-Baylis-Hillman reactions of aryl-substituted imines and alkyl vinyl ketones followed by Michael additions of imides and then epimerization.
| Original language | English |
|---|---|
| Pages (from-to) | 2888-2891 |
| Number of pages | 4 |
| Journal | Journal of Organic Chemistry |
| Volume | 76 |
| Issue number | 8 |
| DOIs | |
| Publication status | Published - 2011 Apr 15 |
ASJC Scopus subject areas
- Organic Chemistry
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CCDC 785233: Experimental Crystal Structure Determination
Syu, S. (Creator), Lee, Y. (Creator), Jang, Y. (Creator) & Lin, W. (Creator), Unknown Publisher, 2012
DOI: 10.5517/ccvc33d, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccvc33d&sid=DataCite
Dataset
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CCDC 785230: Experimental Crystal Structure Determination
Syu, S. (Creator), Lee, Y. (Creator), Jang, Y. (Creator) & Lin, W. (Creator), Unknown Publisher, 2012
DOI: 10.5517/ccvc309, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccvc309&sid=DataCite
Dataset
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CCDC 785236: Experimental Crystal Structure Determination
Syu, S. (Creator), Lee, Y. (Creator), Jang, Y. (Creator) & Lin, W. (Creator), Unknown Publisher, 2012
DOI: 10.5517/ccvc36h, http://www.ccdc.cam.ac.uk/services/structure_request?id=doi:10.5517/ccvc36h&sid=DataCite
Dataset