Organocatalytic tandem three-component reaction of imine, alkyl vinyl ketone, and imide via aza-baylis-hillman reaction

Siang En Syu, Yu Ting Lee, Yeong Jiunn Jang, Wen-Wei Lin

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

A highly chemoselective PPh3-catalyzed three-component reaction of an imine, alkyl vinyl ketone, and phthalimide or succinimide is developed. Various highly functional adducts with high diastereoselectivities can be generated via aza-Morita-Baylis-Hillman reactions of aryl-substituted imines and alkyl vinyl ketones followed by Michael additions of imides and then epimerization.

Original languageEnglish
Pages (from-to)2888-2891
Number of pages4
JournalJournal of Organic Chemistry
Volume76
Issue number8
DOIs
Publication statusPublished - 2011 Apr 15

ASJC Scopus subject areas

  • Organic Chemistry

Fingerprint Dive into the research topics of 'Organocatalytic tandem three-component reaction of imine, alkyl vinyl ketone, and imide via aza-baylis-hillman reaction'. Together they form a unique fingerprint.

  • Cite this