Optimization of the separation of malachite green in water by capillary electrophoresis Raman spectroscopy (CE-RS) based on the stacking and sweeping modes

Chih Hsin Tsai, Jia Der Lin, Cheng Huang Lin*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

54 Citations (Scopus)

Abstract

A capillary electrophoresis Raman spectroscopy (CE-RS) method based on the stacking and sweeping modes are described. A non-fluorescent compound (malachite green, MG; crystal violet, CV) and a doubled Nd:YAG laser (532 nm, 300 mW) were selected as the model compound and light source, respectively. In order to carry out a quantitative and analysis of MG, a monochromator was used to collect the specific Raman line at 1616 cm-1 (the N-φ and C-C stretching, corresponding to 582 nm when the wavelength of the exciting source is 532 nm). The limit of detection (LOD) for MG was 1.6 × 10-5 and 1.1 × 10-5 M, respectively, based on the CZE and MEKC modes. This could be improved to 3.4 × 10-7 and 5.3 × 10-9 M, respectively, when the stacking and sweeping modes were applied. The method was also extended to the determination of MG in an actual sample.

Original languageEnglish
Pages (from-to)368-372
Number of pages5
JournalTalanta
Volume72
Issue number2
DOIs
Publication statusPublished - 2007 Apr 30

Keywords

  • Capillary electrophoresis
  • Crystal violet
  • Malachite green
  • Raman spectroscopy
  • Stacking
  • Sweeping

ASJC Scopus subject areas

  • Analytical Chemistry

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