One-sample measurement in laser nephelometric immunoassay using magnetic nanoparticles

S. Y. Yang, R. M. Wu, Z. F. Jian, H. E. Horng*, Chin Yih Hong, H. C. Yang

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)

Abstract

In contrast to the type of two-sample measurement used in conventional nephelometric immunoassay, a methodology to achieve a one-sample nephelometric immunoassay is developed in this work. Magnetic nanoparticles instead of latex particles are used as scattering centers. The experimental results show that the sensitivity of assaying avidin or c-reactive protein increased about three times under the action of the magnetic field in nephelometric immunoassay using magnetic nanoparticles.

Original languageEnglish
Article number244102
JournalApplied Physics Letters
Volume89
Issue number24
DOIs
Publication statusPublished - 2006

ASJC Scopus subject areas

  • Physics and Astronomy (miscellaneous)

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