One-sample measurement in laser nephelometric immunoassay using magnetic nanoparticles

S. Y. Yang, R. M. Wu, Z. F. Jian, H. E. Horng, Chin Yih Hong, H. C. Yang

    Research output: Contribution to journalArticlepeer-review

    5 Citations (Scopus)

    Abstract

    In contrast to the type of two-sample measurement used in conventional nephelometric immunoassay, a methodology to achieve a one-sample nephelometric immunoassay is developed in this work. Magnetic nanoparticles instead of latex particles are used as scattering centers. The experimental results show that the sensitivity of assaying avidin or c-reactive protein increased about three times under the action of the magnetic field in nephelometric immunoassay using magnetic nanoparticles.

    Original languageEnglish
    Article number244102
    JournalApplied Physics Letters
    Volume89
    Issue number24
    DOIs
    Publication statusPublished - 2006 Dec 29

    ASJC Scopus subject areas

    • Physics and Astronomy (miscellaneous)

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