One-sample measurement in laser nephelometric immunoassay using magnetic nanoparticles

S. Y. Yang, R. M. Wu, Z. F. Jian, H. E. Horng, Chin Yih Hong, H. C. Yang

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Abstract

In contrast to the type of two-sample measurement used in conventional nephelometric immunoassay, a methodology to achieve a one-sample nephelometric immunoassay is developed in this work. Magnetic nanoparticles instead of latex particles are used as scattering centers. The experimental results show that the sensitivity of assaying avidin or c-reactive protein increased about three times under the action of the magnetic field in nephelometric immunoassay using magnetic nanoparticles.

Original languageEnglish
Article number244102
JournalApplied Physics Letters
Volume89
Issue number24
DOIs
Publication statusPublished - 2006 Dec 29

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ASJC Scopus subject areas

  • Physics and Astronomy (miscellaneous)

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