"On-Water"-promoted C-alkylation of indoles with 2-aryl-3-nitro-2H-chromenes under catalyst-free conditions

Pateliya Mujjamil Habib; Veerababurao Kavala; B. Rama Raju; Chun Wei Kuo; Wen Chang Huang; Ching Fa Yao

doi:10.1002/ejoc.200900207

"On-Water"-promoted C-alkylation of indoles with 2-aryl-3-nitro-2H-chromenes under catalyst-free conditions

Pateliya Mujjamil Habib, Veerababurao Kavala, B. Rama Raju, Chun Wei Kuo, Wen Chang Huang, Ching Fa Yao^*

^*Corresponding author for this work

Department of Chemistry

Research output: Contribution to journal › Article › peer-review

33 Citations (Scopus)

Abstract

An environmentally benign, method for the synthesis of indolyl(nitro) chromans from indoles and 2-aryl-3-nit:ro-2Hchromenes under catalyst-free conditions by use of an "onwater" concept is described, The salient features of the methodology are its clean, reaction conditions, the eco-friendly medium, and the easy isolation and excellent diastereoselectivities of the products,

Original language	English
Pages (from-to)	4503-4514
Number of pages	12
Journal	European Journal of Organic Chemistry
Issue number	26
DOIs	https://doi.org/10.1002/ejoc.200900207
Publication status	Published - 2009 Sept

Keywords

"on-water" chemistry
2h-chromenes
Alkylation
Green chemistry
Indoles
Synthetic methods

ASJC Scopus subject areas

Physical and Theoretical Chemistry
Organic Chemistry

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10.1002/ejoc.200900207

Cite this

@article{3b1ce89ea12c438faa6edba0e8171ce3,

title = "{"}On-Water{"}-promoted C-alkylation of indoles with 2-aryl-3-nitro-2H-chromenes under catalyst-free conditions",

abstract = "An environmentally benign, method for the synthesis of indolyl(nitro) chromans from indoles and 2-aryl-3-nit:ro-2Hchromenes under catalyst-free conditions by use of an {"}onwater{"} concept is described, The salient features of the methodology are its clean, reaction conditions, the eco-friendly medium, and the easy isolation and excellent diastereoselectivities of the products,",

keywords = "{"}on-water{"} chemistry, 2h-chromenes, Alkylation, Green chemistry, Indoles, Synthetic methods",

author = "Habib, {Pateliya Mujjamil} and Veerababurao Kavala and {Rama Raju}, B. and Kuo, {Chun Wei} and Huang, {Wen Chang} and Yao, {Ching Fa}",

year = "2009",

month = sep,

doi = "10.1002/ejoc.200900207",

language = "English",

pages = "4503--4514",

journal = "European Journal of Organic Chemistry",

issn = "1434-193X",

publisher = "Wiley-VCH Verlag",

number = "26",

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T1 - "On-Water"-promoted C-alkylation of indoles with 2-aryl-3-nitro-2H-chromenes under catalyst-free conditions

AU - Habib, Pateliya Mujjamil

AU - Kavala, Veerababurao

AU - Rama Raju, B.

AU - Kuo, Chun Wei

AU - Huang, Wen Chang

AU - Yao, Ching Fa

PY - 2009/9

Y1 - 2009/9

N2 - An environmentally benign, method for the synthesis of indolyl(nitro) chromans from indoles and 2-aryl-3-nit:ro-2Hchromenes under catalyst-free conditions by use of an "onwater" concept is described, The salient features of the methodology are its clean, reaction conditions, the eco-friendly medium, and the easy isolation and excellent diastereoselectivities of the products,

AB - An environmentally benign, method for the synthesis of indolyl(nitro) chromans from indoles and 2-aryl-3-nit:ro-2Hchromenes under catalyst-free conditions by use of an "onwater" concept is described, The salient features of the methodology are its clean, reaction conditions, the eco-friendly medium, and the easy isolation and excellent diastereoselectivities of the products,

KW - "on-water" chemistry

KW - 2h-chromenes

KW - Alkylation

KW - Green chemistry

KW - Indoles

KW - Synthetic methods

UR - http://www.scopus.com/inward/record.url?scp=69449106910&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=69449106910&partnerID=8YFLogxK

U2 - 10.1002/ejoc.200900207

DO - 10.1002/ejoc.200900207

M3 - Article

AN - SCOPUS:69449106910

SN - 1434-193X

SP - 4503

EP - 4514

JO - European Journal of Organic Chemistry

JF - European Journal of Organic Chemistry

IS - 26

ER -

"On-Water"-promoted C-alkylation of indoles with 2-aryl-3-nitro-2H-chromenes under catalyst-free conditions

Abstract

Keywords

ASJC Scopus subject areas

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CCDC 699102: Experimental Crystal Structure Determination

CCDC 728662: Experimental Crystal Structure Determination

CCDC 699101: Experimental Crystal Structure Determination

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"On-Water"-promoted C-alkylation of indoles with 2-aryl-3-nitro-2H-chromenes under catalyst-free conditions

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Datasets

CCDC 699102: Experimental Crystal Structure Determination

CCDC 728662: Experimental Crystal Structure Determination

CCDC 699101: Experimental Crystal Structure Determination

Cite this