"On-Water"-promoted C-alkylation of indoles with 2-aryl-3-nitro-2H-chromenes under catalyst-free conditions

Pateliya Mujjamil Habib, Veerababurao Kavala, B. Rama Raju, Chun Wei Kuo, Wen Chang Huang, Ching-Fa Yao

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30 Citations (Scopus)

Abstract

An environmentally benign, method for the synthesis of indolyl(nitro) chromans from indoles and 2-aryl-3-nit:ro-2Hchromenes under catalyst-free conditions by use of an "onwater" concept is described, The salient features of the methodology are its clean, reaction conditions, the eco-friendly medium, and the easy isolation and excellent diastereoselectivities of the products,

Original languageEnglish
Pages (from-to)4503-4514
Number of pages12
JournalEuropean Journal of Organic Chemistry
Issue number26
DOIs
Publication statusPublished - 2009 Sep 1

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Keywords

  • "on-water" chemistry
  • 2h-chromenes
  • Alkylation
  • Green chemistry
  • Indoles
  • Synthetic methods

ASJC Scopus subject areas

  • Physical and Theoretical Chemistry
  • Organic Chemistry

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