Abstract
An environmentally benign, method for the synthesis of indolyl(nitro) chromans from indoles and 2-aryl-3-nit:ro-2Hchromenes under catalyst-free conditions by use of an "onwater" concept is described, The salient features of the methodology are its clean, reaction conditions, the eco-friendly medium, and the easy isolation and excellent diastereoselectivities of the products,
| Original language | English |
|---|---|
| Pages (from-to) | 4503-4514 |
| Number of pages | 12 |
| Journal | European Journal of Organic Chemistry |
| Issue number | 26 |
| DOIs | |
| Publication status | Published - 2009 Sep 1 |
Keywords
- "on-water" chemistry
- 2h-chromenes
- Alkylation
- Green chemistry
- Indoles
- Synthetic methods
ASJC Scopus subject areas
- Physical and Theoretical Chemistry
- Organic Chemistry
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Cite this
Habib, P. M., Kavala, V., Rama Raju, B., Kuo, C. W., Huang, W. C., & Yao, C-F. (2009). "On-Water"-promoted C-alkylation of indoles with 2-aryl-3-nitro-2H-chromenes under catalyst-free conditions. European Journal of Organic Chemistry, (26), 4503-4514. https://doi.org/10.1002/ejoc.200900207