"On-Water"-promoted C-alkylation of indoles with 2-aryl-3-nitro-2H-chromenes under catalyst-free conditions

Pateliya Mujjamil Habib; Veerababurao Kavala; B. Rama Raju; Chun Wei Kuo; Wen Chang Huang; Ching-Fa Yao

doi:10.1002/ejoc.200900207

"On-Water"-promoted C-alkylation of indoles with 2-aryl-3-nitro-2H-chromenes under catalyst-free conditions

Pateliya Mujjamil Habib, Veerababurao Kavala, B. Rama Raju, Chun Wei Kuo, Wen Chang Huang, Ching-Fa Yao

Department of Chemistry

Research output: Contribution to journal › Article

30 Citations (Scopus)

Abstract

An environmentally benign, method for the synthesis of indolyl(nitro) chromans from indoles and 2-aryl-3-nit:ro-2Hchromenes under catalyst-free conditions by use of an "onwater" concept is described, The salient features of the methodology are its clean, reaction conditions, the eco-friendly medium, and the easy isolation and excellent diastereoselectivities of the products,

Original language	English
Pages (from-to)	4503-4514
Number of pages	12
Journal	European Journal of Organic Chemistry
Issue number	26
DOIs	https://doi.org/10.1002/ejoc.200900207
Publication status	Published - 2009 Sep 1

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Keywords

"on-water" chemistry
2h-chromenes
Alkylation
Green chemistry
Indoles
Synthetic methods

ASJC Scopus subject areas

Physical and Theoretical Chemistry
Organic Chemistry

Cite this

Habib, P. M., Kavala, V., Rama Raju, B., Kuo, C. W., Huang, W. C., & Yao, C-F. (2009). "On-Water"-promoted C-alkylation of indoles with 2-aryl-3-nitro-2H-chromenes under catalyst-free conditions. European Journal of Organic Chemistry, (26), 4503-4514. https://doi.org/10.1002/ejoc.200900207

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10.1002/ejoc.200900207