"On-Water"-promoted C-alkylation of indoles with 2-aryl-3-nitro-2H-chromenes under catalyst-free conditions

Pateliya Mujjamil Habib, Veerababurao Kavala, B. Rama Raju, Chun Wei Kuo, Wen Chang Huang, Ching-Fa Yao

Research output: Contribution to journalArticle

30 Citations (Scopus)

Abstract

An environmentally benign, method for the synthesis of indolyl(nitro) chromans from indoles and 2-aryl-3-nit:ro-2Hchromenes under catalyst-free conditions by use of an "onwater" concept is described, The salient features of the methodology are its clean, reaction conditions, the eco-friendly medium, and the easy isolation and excellent diastereoselectivities of the products,

Original languageEnglish
Pages (from-to)4503-4514
Number of pages12
JournalEuropean Journal of Organic Chemistry
Issue number26
DOIs
Publication statusPublished - 2009 Sep 1

Fingerprint

Chromans
Indoles
alkylation
indoles
Alkylation
catalysts
Catalysts
Water
water
isolation
methodology
synthesis
products
5,7-dimethoxy-2-methyl-2H-benzopyran

Keywords

  • "on-water" chemistry
  • 2h-chromenes
  • Alkylation
  • Green chemistry
  • Indoles
  • Synthetic methods

ASJC Scopus subject areas

  • Physical and Theoretical Chemistry
  • Organic Chemistry

Cite this

"On-Water"-promoted C-alkylation of indoles with 2-aryl-3-nitro-2H-chromenes under catalyst-free conditions. / Habib, Pateliya Mujjamil; Kavala, Veerababurao; Rama Raju, B.; Kuo, Chun Wei; Huang, Wen Chang; Yao, Ching-Fa.

In: European Journal of Organic Chemistry, No. 26, 01.09.2009, p. 4503-4514.

Research output: Contribution to journalArticle

Habib, Pateliya Mujjamil ; Kavala, Veerababurao ; Rama Raju, B. ; Kuo, Chun Wei ; Huang, Wen Chang ; Yao, Ching-Fa. / "On-Water"-promoted C-alkylation of indoles with 2-aryl-3-nitro-2H-chromenes under catalyst-free conditions. In: European Journal of Organic Chemistry. 2009 ; No. 26. pp. 4503-4514.
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