On-line identification of 3,4-methylenedioxymethamphetamine in human urine by non-aqueous capillary electrophoresis-fluorescence spectroscopy at 77 K

Yu Lin Chung; Ju Tsung Liu; Cheng Huang Lin

doi:10.1016/S0378-4347(01)00225-0

On-line identification of 3,4-methylenedioxymethamphetamine in human urine by non-aqueous capillary electrophoresis-fluorescence spectroscopy at 77 K

Yu Lin Chung
, Ju Tsung Liu
, Cheng Huang Lin^*

^*Corresponding author for this work

Department of Chemistry

Research output: Contribution to journal › Article › peer-review

16 Citations (Scopus)

Abstract

The analytical profiles for 3,4-methylenedioxymethamphetamine (3,4-MDMA) and related amphetamines in urine samples are described for non-aqueous capillary electrophoresis-fluorescence spectroscopy. 3,4-MDMA was detected and identified on-line, using a cryogenic molecular fluorescence technique at 77 K. Under optimized conditions, baseline separation of the selected compounds was achieved in less than 12 min. Precision was evaluated by measuring the repeatability and intermediate precision of the migration times and corrected peak areas. The non-aqueous CE separation conditions and the spectral characteristics of 3,4-MDMA with respect to solvent and temperature effects are also discussed.

Original language	English
Pages (from-to)	219-226
Number of pages	8
Journal	Journal of Chromatography B: Biomedical Sciences and Applications
Volume	759
Issue number	2
DOIs	https://doi.org/10.1016/S0378-4347(01)00225-0
Publication status	Published - 2001 Aug 15

Keywords

3,4-Methylenedioxymethamphetamine

ASJC Scopus subject areas

General Chemistry

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10.1016/S0378-4347(01)00225-0

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On-line identification of 3,4-methylenedioxymethamphetamine in human urine by non-aqueous capillary electrophoresis-fluorescence spectroscopy at 77 K. / Chung, Yu Lin; Liu, Ju Tsung; Lin, Cheng Huang.
In: Journal of Chromatography B: Biomedical Sciences and Applications, Vol. 759, No. 2, 15.08.2001, p. 219-226.

Research output: Contribution to journal › Article › peer-review

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title = "On-line identification of 3,4-methylenedioxymethamphetamine in human urine by non-aqueous capillary electrophoresis-fluorescence spectroscopy at 77 K",

abstract = "The analytical profiles for 3,4-methylenedioxymethamphetamine (3,4-MDMA) and related amphetamines in urine samples are described for non-aqueous capillary electrophoresis-fluorescence spectroscopy. 3,4-MDMA was detected and identified on-line, using a cryogenic molecular fluorescence technique at 77 K. Under optimized conditions, baseline separation of the selected compounds was achieved in less than 12 min. Precision was evaluated by measuring the repeatability and intermediate precision of the migration times and corrected peak areas. The non-aqueous CE separation conditions and the spectral characteristics of 3,4-MDMA with respect to solvent and temperature effects are also discussed.",

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note = "Funding Information: This work was supported by a grant from the National Science Council of Taiwan under contract No. NSC-89-2113-M-003-016. Permission was obtained from Pharmaceutical Affairs, Department of Health, Taiwan (license No.: ARR089000035). The authors would like to thank the Forensic Science Center (Taiwan Command of the Army Force of Military Police) for generously donating the urine samples and amphetamine standards.",

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doi = "10.1016/S0378-4347(01)00225-0",

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AU - Chung, Yu Lin

AU - Liu, Ju Tsung

AU - Lin, Cheng Huang

N1 - Funding Information: This work was supported by a grant from the National Science Council of Taiwan under contract No. NSC-89-2113-M-003-016. Permission was obtained from Pharmaceutical Affairs, Department of Health, Taiwan (license No.: ARR089000035). The authors would like to thank the Forensic Science Center (Taiwan Command of the Army Force of Military Police) for generously donating the urine samples and amphetamine standards.

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N2 - The analytical profiles for 3,4-methylenedioxymethamphetamine (3,4-MDMA) and related amphetamines in urine samples are described for non-aqueous capillary electrophoresis-fluorescence spectroscopy. 3,4-MDMA was detected and identified on-line, using a cryogenic molecular fluorescence technique at 77 K. Under optimized conditions, baseline separation of the selected compounds was achieved in less than 12 min. Precision was evaluated by measuring the repeatability and intermediate precision of the migration times and corrected peak areas. The non-aqueous CE separation conditions and the spectral characteristics of 3,4-MDMA with respect to solvent and temperature effects are also discussed.

AB - The analytical profiles for 3,4-methylenedioxymethamphetamine (3,4-MDMA) and related amphetamines in urine samples are described for non-aqueous capillary electrophoresis-fluorescence spectroscopy. 3,4-MDMA was detected and identified on-line, using a cryogenic molecular fluorescence technique at 77 K. Under optimized conditions, baseline separation of the selected compounds was achieved in less than 12 min. Precision was evaluated by measuring the repeatability and intermediate precision of the migration times and corrected peak areas. The non-aqueous CE separation conditions and the spectral characteristics of 3,4-MDMA with respect to solvent and temperature effects are also discussed.

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On-line identification of 3,4-methylenedioxymethamphetamine in human urine by non-aqueous capillary electrophoresis-fluorescence spectroscopy at 77 K

Abstract

Keywords

ASJC Scopus subject areas

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