Obesity as a critical issue of breast cancer development

Chia Chien Hsieh, Yu Chen Chou, Chih Hsuan Wang

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

The prevalence of cancer is associated with obese and is estimated up to 20% which was influenced by dietary intake, body fat distribution, and physical activity. Nowadays, obesity is considered as one of the most hazardous factors for the breast cancer of women after menopause. To understand the linking mechanism of cancer and obesity is the critical issue should be addressed, and then to find out and develop new methods to prevent or treat this kind of cancer. Accumulating evidence has shown the possible mechanism, such as genetic susceptibility, low grade inflammation, immune system dysfunction, oxidative stress, and circumambient adipocyte crosstalk with cancer cell. This review was present an update summary of obesity-driven changes and tumor microenvironment, as well as release signaling, growth factors, and inflammatory cytokines were also highlighted.

Original languageEnglish
Title of host publicationBreast Cancer
Subtitle of host publicationRisk Assessment, Treatment and New Developments
PublisherNova Science Publishers, Inc.
Pages17-32
Number of pages16
ISBN (Electronic)9781634852159
ISBN (Print)9781634851848
Publication statusPublished - 2016 Jan 1

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Obesity
Breast Neoplasms
Neoplasms
Body Fat Distribution
Tumor Microenvironment
Genetic Predisposition to Disease
Menopause
Adipocytes
Immune System
Intercellular Signaling Peptides and Proteins
Oxidative Stress
Exercise
Cytokines
Inflammation

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Hsieh, C. C., Chou, Y. C., & Wang, C. H. (2016). Obesity as a critical issue of breast cancer development. In Breast Cancer: Risk Assessment, Treatment and New Developments (pp. 17-32). Nova Science Publishers, Inc..

Obesity as a critical issue of breast cancer development. / Hsieh, Chia Chien; Chou, Yu Chen; Wang, Chih Hsuan.

Breast Cancer: Risk Assessment, Treatment and New Developments. Nova Science Publishers, Inc., 2016. p. 17-32.

Research output: Chapter in Book/Report/Conference proceedingChapter

Hsieh, CC, Chou, YC & Wang, CH 2016, Obesity as a critical issue of breast cancer development. in Breast Cancer: Risk Assessment, Treatment and New Developments. Nova Science Publishers, Inc., pp. 17-32.
Hsieh CC, Chou YC, Wang CH. Obesity as a critical issue of breast cancer development. In Breast Cancer: Risk Assessment, Treatment and New Developments. Nova Science Publishers, Inc. 2016. p. 17-32
Hsieh, Chia Chien ; Chou, Yu Chen ; Wang, Chih Hsuan. / Obesity as a critical issue of breast cancer development. Breast Cancer: Risk Assessment, Treatment and New Developments. Nova Science Publishers, Inc., 2016. pp. 17-32
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