Nucleosides XIII. Facile synthesis of 4-amino-1-(2-deoxy-β-D- ribofuranosyl)quinazolin-2-one as a 2′-deoxycytidine analog for oligonucleotide synthesis

Tun Cheng Chien, Chien Shu Chen, Ji Wang Chern

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

4-Amino-1-(2-deoxy-β-D-ribofuranosyl)quinazo1in-2-one (4) was prepared by Barton deoxygenation from 4-amino-1-(β-D-ribofuranosyl)quinazolin-2-one (3) as a 2′-deoxycytidine analog.

Original languageEnglish
Pages (from-to)1237-1244
Number of pages8
JournalJournal of the Chinese Chemical Society
Volume52
Issue number6
DOIs
Publication statusPublished - 2005 Jan 1

Keywords

  • 2′-Deoxycytidine
  • Barton deoxygenation
  • Cytidine
  • Markiewicz silylation
  • Quinazolinone

ASJC Scopus subject areas

  • Chemistry(all)

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