Novel trypsin-FITC@MOF bioreactor efficiently catalyzes protein digestion

Wan Ling Liu, Sheng Han Lo, Brenda Singco, Chun Chuen Yang, Hsi Ya Huang*, Chia Her Lin

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

144 Citations (Scopus)


A simple nanoporous metal organic framework (MOF) bioreactor preparation via a low energy 30 minute vortex as driving force to immobilize trypsin enzyme is presented. No chemical modifications were employed thus organic wastes were eliminated. The digestion efficiency of this trypsin bioreactor is exceptionally high, even when reused. This "green" synthesis procedure produced a "green" bioreactor.

Original languageEnglish
Pages (from-to)928-932
Number of pages5
JournalJournal of Materials Chemistry B
Issue number7
Publication statusPublished - 2013 Feb 21
Externally publishedYes

ASJC Scopus subject areas

  • Chemistry(all)
  • Biomedical Engineering
  • Materials Science(all)


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