Novel synthesis of indolylquinoline derivatives via the C-alkylation of Baylis-Hillman adducts

Chintakunta Ramesh; Veerababurao Kavala; B. Rama Raju; Chun Wei Kuo; Ching Fa Yao

doi:10.1016/j.tetlet.2009.04.064

Novel synthesis of indolylquinoline derivatives via the C-alkylation of Baylis-Hillman adducts

Chintakunta Ramesh, Veerababurao Kavala, B. Rama Raju, Chun Wei Kuo, Ching Fa Yao

Department of Chemistry

Research output: Contribution to journal › Article › peer-review

24 Citations (Scopus)

Abstract

A new and simple method for the C-alkylation of indoles by various Baylis-Hillman adducts and the one-pot reductive cyclization of C-alkylated indole derivatives generated from 2-nitro-Baylis-Hillman adduct to form indolylquinoline derivatives is described.

Original language	English
Pages (from-to)	4037-4041
Number of pages	5
Journal	Tetrahedron Letters
Volume	50
Issue number	28
DOIs	https://doi.org/10.1016/j.tetlet.2009.04.064
Publication status	Published - 2009 Jul 15

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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title = "Novel synthesis of indolylquinoline derivatives via the C-alkylation of Baylis-Hillman adducts",

abstract = "A new and simple method for the C-alkylation of indoles by various Baylis-Hillman adducts and the one-pot reductive cyclization of C-alkylated indole derivatives generated from 2-nitro-Baylis-Hillman adduct to form indolylquinoline derivatives is described.",

author = "Chintakunta Ramesh and Veerababurao Kavala and Raju, {B. Rama} and Kuo, {Chun Wei} and Yao, {Ching Fa}",

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AU - Ramesh, Chintakunta

AU - Kavala, Veerababurao

AU - Raju, B. Rama

AU - Kuo, Chun Wei

AU - Yao, Ching Fa

PY - 2009/7/15

Y1 - 2009/7/15

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AB - A new and simple method for the C-alkylation of indoles by various Baylis-Hillman adducts and the one-pot reductive cyclization of C-alkylated indole derivatives generated from 2-nitro-Baylis-Hillman adduct to form indolylquinoline derivatives is described.

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DO - 10.1016/j.tetlet.2009.04.064

M3 - Article

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EP - 4041

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