Novel synthesis of indolylquinoline derivatives via the C-alkylation of Baylis-Hillman adducts

Chintakunta Ramesh, Veerababurao Kavala, B. Rama Raju, Chun Wei Kuo, Ching-Fa Yao

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

A new and simple method for the C-alkylation of indoles by various Baylis-Hillman adducts and the one-pot reductive cyclization of C-alkylated indole derivatives generated from 2-nitro-Baylis-Hillman adduct to form indolylquinoline derivatives is described.

Original languageEnglish
Pages (from-to)4037-4041
Number of pages5
JournalTetrahedron Letters
Volume50
Issue number28
DOIs
Publication statusPublished - 2009 Jul 15

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Indoles
Alkylation
Cyclization
Derivatives
indole

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

Cite this

Novel synthesis of indolylquinoline derivatives via the C-alkylation of Baylis-Hillman adducts. / Ramesh, Chintakunta; Kavala, Veerababurao; Raju, B. Rama; Kuo, Chun Wei; Yao, Ching-Fa.

In: Tetrahedron Letters, Vol. 50, No. 28, 15.07.2009, p. 4037-4041.

Research output: Contribution to journalArticle

Ramesh, Chintakunta ; Kavala, Veerababurao ; Raju, B. Rama ; Kuo, Chun Wei ; Yao, Ching-Fa. / Novel synthesis of indolylquinoline derivatives via the C-alkylation of Baylis-Hillman adducts. In: Tetrahedron Letters. 2009 ; Vol. 50, No. 28. pp. 4037-4041.
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