Non-invasive and time-dependent blood-sugar monitoring via breath-derived CO2 correlation using gas chromatograph with a milli-whistle gas analyzer

Cheng Huang Lin; Luo Xian Wu; Kuan Hao Chen; Hsu Feng Lo; King Chuen Lin; Toshio Kasai; Chien Chung Chen; Chung Hung Shih; Maria Carla Manzano; Gil Nonato Santos; Enrique Manzano; Derrick Ethelbhert Yu

doi:10.2116/ANALSCI.19P407

Non-invasive and time-dependent blood-sugar monitoring via breath-derived CO₂ correlation using gas chromatograph with a milli-whistle gas analyzer

Cheng Huang Lin^*, Luo Xian Wu, Kuan Hao Chen, Hsu Feng Lo, King Chuen Lin, Toshio Kasai, Chien Chung Chen, Chung Hung Shih, Maria Carla Manzano, Gil Nonato Santos, Enrique Manzano, Derrick Ethelbhert Yu

^*Corresponding author for this work

Department of Chemistry

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

A clear and positive correlation between the CO₂ concentration and the blood-sugar level has been observed via a noninvasive and time-dependent monitoring of CO₂ concentration from human breath, which is carried out by using a homemade gas chromatography (GC)/milli-whistle compact analyzer. The time-dependent sampling of the CO₂ concentration correlated between 5.0 to 5.6% (1% = 104 ppm) in accordance with blood-sugar level variations of 80 to 110 mg/dL. The analytical method results in a rapid, continuous and non-invasive determination of blood-sugar level via measurement of the CO₂ concentration exhaled from the lungs.

Original language	English
Article number	P407
Pages (from-to)	739-743
Number of pages	5
Journal	Analytical Sciences
Volume	36
Issue number	6
DOIs	https://doi.org/10.2116/ANALSCI.19P407
Publication status	Published - 2020

Keywords

Co
Gas chromatography/milli-whistle compact analyzer
Human breath monitoring
Non-invasive blood-sugar level measurement
Respiration
Rq index

ASJC Scopus subject areas

Analytical Chemistry

Access to Document

10.2116/ANALSCI.19P407

Cite this

Lin, C. H., Wu, L. X., Chen, K. H., Lo, H. F., Lin, K. C., Kasai, T., Chen, C. C., Shih, C. H., Manzano, M. C., Santos, G. N., Manzano, E., & Yu, D. E. (2020). Non-invasive and time-dependent blood-sugar monitoring via breath-derived CO₂ correlation using gas chromatograph with a milli-whistle gas analyzer. Analytical Sciences, 36(6), 739-743. Article P407. https://doi.org/10.2116/ANALSCI.19P407

Lin, CH, Wu, LX, Chen, KH, Lo, HF, Lin, KC, Kasai, T, Chen, CC, Shih, CH, Manzano, MC, Santos, GN, Manzano, E & Yu, DE 2020, 'Non-invasive and time-dependent blood-sugar monitoring via breath-derived CO₂ correlation using gas chromatograph with a milli-whistle gas analyzer', Analytical Sciences, vol. 36, no. 6, P407, pp. 739-743. https://doi.org/10.2116/ANALSCI.19P407

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abstract = "A clear and positive correlation between the CO2 concentration and the blood-sugar level has been observed via a noninvasive and time-dependent monitoring of CO2 concentration from human breath, which is carried out by using a homemade gas chromatography (GC)/milli-whistle compact analyzer. The time-dependent sampling of the CO2 concentration correlated between 5.0 to 5.6% (1% = 104 ppm) in accordance with blood-sugar level variations of 80 to 110 mg/dL. The analytical method results in a rapid, continuous and non-invasive determination of blood-sugar level via measurement of the CO2 concentration exhaled from the lungs.",

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