Non-invasive and time-dependent blood-sugar monitoring via breath-derived CO2 correlation using gas chromatograph with a milli-whistle gas analyzer

Cheng Huang Lin, Luo Xian Wu, Kuan Hao Chen, Hsu Feng Lo, King Chuen Lin, Toshio Kasai, Chien Chung Chen, Chung Hung Shih, Maria Carla Manzano, Gil Nonato Santos, Enrique Manzano, Derrick Ethelbhert Yu

Research output: Contribution to journalArticle

Abstract

A clear and positive correlation between the CO2 concentration and the blood-sugar level has been observed via a noninvasive and time-dependent monitoring of CO2 concentration from human breath, which is carried out by using a homemade gas chromatography (GC)/milli-whistle compact analyzer. The time-dependent sampling of the CO2 concentration correlated between 5.0 to 5.6% (1% = 104 ppm) in accordance with blood-sugar level variations of 80 to 110 mg/dL. The analytical method results in a rapid, continuous and non-invasive determination of blood-sugar level via measurement of the CO2 concentration exhaled from the lungs.

Original languageEnglish
Article numberP407
Pages (from-to)739-743
Number of pages5
JournalAnalytical Sciences
Volume36
Issue number6
DOIs
Publication statusPublished - 2020

Keywords

  • Co
  • Gas chromatography/milli-whistle compact analyzer
  • Human breath monitoring
  • Non-invasive blood-sugar level measurement
  • Respiration
  • Rq index

ASJC Scopus subject areas

  • Analytical Chemistry

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    Lin, C. H., Wu, L. X., Chen, K. H., Lo, H. F., Lin, K. C., Kasai, T., Chen, C. C., Shih, C. H., Manzano, M. C., Santos, G. N., Manzano, E., & Yu, D. E. (2020). Non-invasive and time-dependent blood-sugar monitoring via breath-derived CO2 correlation using gas chromatograph with a milli-whistle gas analyzer. Analytical Sciences, 36(6), 739-743. [P407]. https://doi.org/10.2116/ANALSCI.19P407