TY - JOUR
T1 - Non-apnea sleep disorder increases the risk of periodontal disease
T2 - A retrospective population-based cohort study
AU - Lee, Chun Feng
AU - Lin., Ming Chia
AU - Lin, Cheng Li
AU - Yen, Chia Ming
AU - Chang, Y. J.
AU - Kao, Chia Hung
PY - 2014/4
Y1 - 2014/4
N2 - The aim of this study is to determine whether patients with a non-apnea sleep disorder (NA-SD) and comorbidity have an increased risk of periodontal disease. Methods: Patients newly diagnosed with NA-SDs in 1997 to 2010 were identified as the study cohort from the Taiwan National Health Insurance database. For each patient with NA-SD, two matched controls without sleep disorders were randomly selected for comparison. Results: The overall incidence rate ratio of severe periodontal diseases was 39% higher in the NA-SD cohort than in the comparison cohort (7.93 versus 5.69 per 1,000 person- years), with an adjusted hazard ratio (HR) of 1.36 (95% confidence interval [CI]: 1.30 to 1.43). The effect of NA-SD on the risk of severe periodontal diseases was higher in young and middle-aged patients compared with patients <65 years of age (<35 years of age, HR: 1.13, 95% CI: 1.04 to 1.24; 35 to 49 years of age, HR: 1.73, 95% CI: 1.61 to 1.86; 50 to 64 years of age, HR: 1.69, 95% CI: 1.58 to 1.81; >65, HR: [reference] 1.0). Conclusion: NA-SD might increase the risk of periodontal disease. J Periodontol 2014;85:e65-e71.
AB - The aim of this study is to determine whether patients with a non-apnea sleep disorder (NA-SD) and comorbidity have an increased risk of periodontal disease. Methods: Patients newly diagnosed with NA-SDs in 1997 to 2010 were identified as the study cohort from the Taiwan National Health Insurance database. For each patient with NA-SD, two matched controls without sleep disorders were randomly selected for comparison. Results: The overall incidence rate ratio of severe periodontal diseases was 39% higher in the NA-SD cohort than in the comparison cohort (7.93 versus 5.69 per 1,000 person- years), with an adjusted hazard ratio (HR) of 1.36 (95% confidence interval [CI]: 1.30 to 1.43). The effect of NA-SD on the risk of severe periodontal diseases was higher in young and middle-aged patients compared with patients <65 years of age (<35 years of age, HR: 1.13, 95% CI: 1.04 to 1.24; 35 to 49 years of age, HR: 1.73, 95% CI: 1.61 to 1.86; 50 to 64 years of age, HR: 1.69, 95% CI: 1.58 to 1.81; >65, HR: [reference] 1.0). Conclusion: NA-SD might increase the risk of periodontal disease. J Periodontol 2014;85:e65-e71.
KW - Cohort studies
KW - Comorbidity
KW - National health programs
KW - Nonapnea sleep syndrome
KW - Periodontal disease
KW - Sleep disorders
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U2 - 10.1902/jop.2013.130284
DO - 10.1902/jop.2013.130284
M3 - Article
C2 - 24059676
AN - SCOPUS:84897391628
SN - 0022-3492
VL - 85
SP - e65-e71
JO - Journal of Periodontology
JF - Journal of Periodontology
IS - 4
ER -