NBS as an efficient catalyst for the synthesis of 1,5-benzodiazepine derivatives under mild conditions

Chun Wei Kuo; Shivaji V. More; Ching Fa Yao

doi:10.1016/j.tetlet.2006.09.128

NBS as an efficient catalyst for the synthesis of 1,5-benzodiazepine derivatives under mild conditions

Chun Wei Kuo, Shivaji V. More, Ching Fa Yao^*

^*Corresponding author for this work

Department of Chemistry

Research output: Contribution to journal › Article › peer-review

61 Citations (Scopus)

Abstract

Various biologically important 1,5-benzodiazepine derivatives were efficiently synthesized in excellent yields using catalytic amounts of NBS (10 mol %). This inexpensive, nontoxic, and readily available catalyst efficiently catalyzes the condensation of several aromatic as well as aliphatic ketones with substituted o-phenylenediamines.

Original language	English
Pages (from-to)	8523-8528
Number of pages	6
Journal	Tetrahedron Letters
Volume	47
Issue number	48
DOIs	https://doi.org/10.1016/j.tetlet.2006.09.128
Publication status	Published - 2006 Nov 27

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

Access to Document

10.1016/j.tetlet.2006.09.128

Cite this

@article{b4b29d7560264ee1b1b0ec834112b988,

title = "NBS as an efficient catalyst for the synthesis of 1,5-benzodiazepine derivatives under mild conditions",

abstract = "Various biologically important 1,5-benzodiazepine derivatives were efficiently synthesized in excellent yields using catalytic amounts of NBS (10 mol %). This inexpensive, nontoxic, and readily available catalyst efficiently catalyzes the condensation of several aromatic as well as aliphatic ketones with substituted o-phenylenediamines.",

author = "Kuo, {Chun Wei} and More, {Shivaji V.} and Yao, {Ching Fa}",

note = "Funding Information: The authors thank the National Science Council of the Republic of China for financial support of this work and Dr. Liu Ju-Tsung for GC–MS analysis.",

year = "2006",

month = nov,

day = "27",

doi = "10.1016/j.tetlet.2006.09.128",

language = "English",

volume = "47",

pages = "8523--8528",

journal = "Tetrahedron Letters",

issn = "0040-4039",

publisher = "Elsevier Limited",

number = "48",

}

TY - JOUR

T1 - NBS as an efficient catalyst for the synthesis of 1,5-benzodiazepine derivatives under mild conditions

AU - Kuo, Chun Wei

AU - More, Shivaji V.

AU - Yao, Ching Fa

N1 - Funding Information: The authors thank the National Science Council of the Republic of China for financial support of this work and Dr. Liu Ju-Tsung for GC–MS analysis.

PY - 2006/11/27

Y1 - 2006/11/27

N2 - Various biologically important 1,5-benzodiazepine derivatives were efficiently synthesized in excellent yields using catalytic amounts of NBS (10 mol %). This inexpensive, nontoxic, and readily available catalyst efficiently catalyzes the condensation of several aromatic as well as aliphatic ketones with substituted o-phenylenediamines.

AB - Various biologically important 1,5-benzodiazepine derivatives were efficiently synthesized in excellent yields using catalytic amounts of NBS (10 mol %). This inexpensive, nontoxic, and readily available catalyst efficiently catalyzes the condensation of several aromatic as well as aliphatic ketones with substituted o-phenylenediamines.

UR - http://www.scopus.com/inward/record.url?scp=33750287620&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=33750287620&partnerID=8YFLogxK

U2 - 10.1016/j.tetlet.2006.09.128

DO - 10.1016/j.tetlet.2006.09.128

M3 - Article

AN - SCOPUS:33750287620

SN - 0040-4039

VL - 47

SP - 8523

EP - 8528

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 48

ER -

NBS as an efficient catalyst for the synthesis of 1,5-benzodiazepine derivatives under mild conditions

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this