Nanoscale imaging of biomolecules by controlled carbon nanotube probes

Yuan Chih Chang; Chia Seng Chang; Dau Chung Wang; Ming Hui Lee; Ting Fang Wang; Mei Yueh Wu; Tsu Yi Fu; Tien T. Tsong

doi:10.1143/JJAP.43.4517

Nanoscale imaging of biomolecules by controlled carbon nanotube probes

Yuan Chih Chang, Chia Seng Chang^*, Dau Chung Wang, Ming Hui Lee, Ting Fang Wang, Mei Yueh Wu, Tsu Yi Fu, Tien T. Tsong

^*Corresponding author for this work

Department of Physics

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Abstract

We use a carbon nanotube (CNT) probe to observe the details in double-stranded deoxyribonucleic acid (DNA) and proteins under atomic force microscopy (AFM) tapping mode in air. The DNA has periodic helical turns of approximately 4 nm interval. Fine ring like and helical structures in the proteins adsorbed on graphite have also been resolved. These results cannot be reproduced using conventional AFM silicon probes. The superiority of the CNT probe applied with the AFM tapping mode lies in both the unique mechanical and chemical properties of the carbon nanotube, and in our ability to tailor the length and adjust the angle of the CNT probe attached to a commercial AFM tip.

Original language	English
Pages (from-to)	4517-4520
Number of pages	4
Journal	Japanese Journal of Applied Physics, Part 1: Regular Papers and Short Notes and Review Papers
Volume	43
Issue number	7 B
DOIs	https://doi.org/10.1143/JJAP.43.4517
Publication status	Published - 2004 Jul

Keywords

Atomic force microscopy
Carbon nanotube
DNA
Protein

ASJC Scopus subject areas

General Engineering
General Physics and Astronomy

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10.1143/JJAP.43.4517

Cite this

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abstract = "We use a carbon nanotube (CNT) probe to observe the details in double-stranded deoxyribonucleic acid (DNA) and proteins under atomic force microscopy (AFM) tapping mode in air. The DNA has periodic helical turns of approximately 4 nm interval. Fine ring like and helical structures in the proteins adsorbed on graphite have also been resolved. These results cannot be reproduced using conventional AFM silicon probes. The superiority of the CNT probe applied with the AFM tapping mode lies in both the unique mechanical and chemical properties of the carbon nanotube, and in our ability to tailor the length and adjust the angle of the CNT probe attached to a commercial AFM tip.",

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AU - Chang, Yuan Chih

AU - Chang, Chia Seng

AU - Wang, Dau Chung

AU - Lee, Ming Hui

AU - Wang, Ting Fang

AU - Wu, Mei Yueh

AU - Fu, Tsu Yi

AU - Tsong, Tien T.

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AB - We use a carbon nanotube (CNT) probe to observe the details in double-stranded deoxyribonucleic acid (DNA) and proteins under atomic force microscopy (AFM) tapping mode in air. The DNA has periodic helical turns of approximately 4 nm interval. Fine ring like and helical structures in the proteins adsorbed on graphite have also been resolved. These results cannot be reproduced using conventional AFM silicon probes. The superiority of the CNT probe applied with the AFM tapping mode lies in both the unique mechanical and chemical properties of the carbon nanotube, and in our ability to tailor the length and adjust the angle of the CNT probe attached to a commercial AFM tip.

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KW - Carbon nanotube

KW - DNA

KW - Protein

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Nanoscale imaging of biomolecules by controlled carbon nanotube probes

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Keywords

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