Abstract
We use a carbon nanotube (CNT) probe to observe the details in double-stranded deoxyribonucleic acid (DNA) and proteins under atomic force microscopy (AFM) tapping mode in air. The DNA has periodic helical turns of approximately 4 nm interval. Fine ring like and helical structures in the proteins adsorbed on graphite have also been resolved. These results cannot be reproduced using conventional AFM silicon probes. The superiority of the CNT probe applied with the AFM tapping mode lies in both the unique mechanical and chemical properties of the carbon nanotube, and in our ability to tailor the length and adjust the angle of the CNT probe attached to a commercial AFM tip.
| Original language | English |
|---|---|
| Pages (from-to) | 4517-4520 |
| Number of pages | 4 |
| Journal | Japanese Journal of Applied Physics, Part 1: Regular Papers and Short Notes and Review Papers |
| Volume | 43 |
| Issue number | 7 B |
| DOIs | |
| Publication status | Published - 2004 Jul 1 |
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Keywords
- Atomic force microscopy
- Carbon nanotube
- DNA
- Protein
ASJC Scopus subject areas
- Engineering(all)
- Physics and Astronomy(all)
Cite this
Nanoscale imaging of biomolecules by controlled carbon nanotube probes. / Chang, Yuan Chih; Chang, Chia Seng; Wang, Dau Chung; Lee, Ming Hui; Wang, Ting Fang; Wu, Mei Yueh; Fu, Tsu Yi; Tsong, Tien T.
In: Japanese Journal of Applied Physics, Part 1: Regular Papers and Short Notes and Review Papers, Vol. 43, No. 7 B, 01.07.2004, p. 4517-4520.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Nanoscale imaging of biomolecules by controlled carbon nanotube probes
AU - Chang, Yuan Chih
AU - Chang, Chia Seng
AU - Wang, Dau Chung
AU - Lee, Ming Hui
AU - Wang, Ting Fang
AU - Wu, Mei Yueh
AU - Fu, Tsu Yi
AU - Tsong, Tien T.
PY - 2004/7/1
Y1 - 2004/7/1
N2 - We use a carbon nanotube (CNT) probe to observe the details in double-stranded deoxyribonucleic acid (DNA) and proteins under atomic force microscopy (AFM) tapping mode in air. The DNA has periodic helical turns of approximately 4 nm interval. Fine ring like and helical structures in the proteins adsorbed on graphite have also been resolved. These results cannot be reproduced using conventional AFM silicon probes. The superiority of the CNT probe applied with the AFM tapping mode lies in both the unique mechanical and chemical properties of the carbon nanotube, and in our ability to tailor the length and adjust the angle of the CNT probe attached to a commercial AFM tip.
AB - We use a carbon nanotube (CNT) probe to observe the details in double-stranded deoxyribonucleic acid (DNA) and proteins under atomic force microscopy (AFM) tapping mode in air. The DNA has periodic helical turns of approximately 4 nm interval. Fine ring like and helical structures in the proteins adsorbed on graphite have also been resolved. These results cannot be reproduced using conventional AFM silicon probes. The superiority of the CNT probe applied with the AFM tapping mode lies in both the unique mechanical and chemical properties of the carbon nanotube, and in our ability to tailor the length and adjust the angle of the CNT probe attached to a commercial AFM tip.
KW - Atomic force microscopy
KW - Carbon nanotube
KW - DNA
KW - Protein
UR - http://www.scopus.com/inward/record.url?scp=5144228655&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=5144228655&partnerID=8YFLogxK
U2 - 10.1143/JJAP.43.4517
DO - 10.1143/JJAP.43.4517
M3 - Article
AN - SCOPUS:5144228655
VL - 43
SP - 4517
EP - 4520
JO - Japanese Journal of Applied Physics, Part 1: Regular Papers & Short Notes
JF - Japanese Journal of Applied Physics, Part 1: Regular Papers & Short Notes
SN - 0021-4922
IS - 7 B
ER -