Nanoscale imaging of biomolecules by controlled carbon nanotube probes

Yuan Chih Chang, Chia Seng Chang, Dau Chung Wang, Ming Hui Lee, Ting Fang Wang, Mei Yueh Wu, Tsu Yi Fu, Tien T. Tsong

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

We use a carbon nanotube (CNT) probe to observe the details in double-stranded deoxyribonucleic acid (DNA) and proteins under atomic force microscopy (AFM) tapping mode in air. The DNA has periodic helical turns of approximately 4 nm interval. Fine ring like and helical structures in the proteins adsorbed on graphite have also been resolved. These results cannot be reproduced using conventional AFM silicon probes. The superiority of the CNT probe applied with the AFM tapping mode lies in both the unique mechanical and chemical properties of the carbon nanotube, and in our ability to tailor the length and adjust the angle of the CNT probe attached to a commercial AFM tip.

Original languageEnglish
Pages (from-to)4517-4520
Number of pages4
JournalJapanese Journal of Applied Physics, Part 1: Regular Papers and Short Notes and Review Papers
Volume43
Issue number7 B
DOIs
Publication statusPublished - 2004 Jul 1

Fingerprint

Biomolecules
Atomic force microscopy
Carbon nanotubes
carbon nanotubes
atomic force microscopy
Imaging techniques
probes
DNA
deoxyribonucleic acid
proteins
Proteins
chemical properties
Chemical properties
Graphite
graphite
mechanical properties
intervals
Silicon
Mechanical properties
rings

Keywords

  • Atomic force microscopy
  • Carbon nanotube
  • DNA
  • Protein

ASJC Scopus subject areas

  • Engineering(all)
  • Physics and Astronomy(all)

Cite this

Nanoscale imaging of biomolecules by controlled carbon nanotube probes. / Chang, Yuan Chih; Chang, Chia Seng; Wang, Dau Chung; Lee, Ming Hui; Wang, Ting Fang; Wu, Mei Yueh; Fu, Tsu Yi; Tsong, Tien T.

In: Japanese Journal of Applied Physics, Part 1: Regular Papers and Short Notes and Review Papers, Vol. 43, No. 7 B, 01.07.2004, p. 4517-4520.

Research output: Contribution to journalArticle

Chang, Yuan Chih ; Chang, Chia Seng ; Wang, Dau Chung ; Lee, Ming Hui ; Wang, Ting Fang ; Wu, Mei Yueh ; Fu, Tsu Yi ; Tsong, Tien T. / Nanoscale imaging of biomolecules by controlled carbon nanotube probes. In: Japanese Journal of Applied Physics, Part 1: Regular Papers and Short Notes and Review Papers. 2004 ; Vol. 43, No. 7 B. pp. 4517-4520.
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