Nanoporous Carbons Derived from Metal-Organic Frameworks as Novel Matrices for Surface-Assisted Laser Desorption/Ionization Mass Spectrometry

Yung Han Shih, Chien Ping Fu, Wan Ling Liu, Chia Her Lin*, Hsi Ya Huang, Shengqian Ma

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

39 Citations (Scopus)

Abstract

Surface-assisted laser desorption/ionization mass spectrometry (SALDI-MS) represents a powerful tool for the analysis of biomolecules, synthetic polymers, and even small organic compounds; its performances largely depend on the type of matrix materials utilized. Here, for the first time the employment of nanoporous carbons derived from metal-organic frameworks (MOFs) as novel matrices for SALDI-MS is demonstrated. The nanoporous carbons derived from MOFs not only circumvent the shortcomings of existing matrix materials but also demonstrate much higher efficiency of laser desorption/ionization for various compounds than any other nanoporous carbons reported so far. A new perspective for the development of matrix materials for SALDI-MS application is therefore provided.

Original languageEnglish
Pages (from-to)2057-2066
Number of pages10
JournalSmall
Volume12
Issue number15
DOIs
Publication statusPublished - 2016 Apr 20
Externally publishedYes

Keywords

  • laser chemistry
  • mass spectrometry
  • metal-organic frameworks
  • nanoporous carbons
  • nanostructures

ASJC Scopus subject areas

  • Biotechnology
  • Biomaterials
  • Chemistry(all)
  • Materials Science(all)

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