Nanopore sequencing of polynucleotides assisted by a rotating electric field

C. M. Chen; E. H. Peng

doi:10.1063/1.1554480

Nanopore sequencing of polynucleotides assisted by a rotating electric field

C. M. Chen^*, E. H. Peng

^*Corresponding author for this work

Department of Physics

Research output: Contribution to journal › Article › peer-review

22 Citations (Scopus)

Abstract

A method to control the translocation processes of polynucleotides through a nanopore, assisted by a rotating electric field was demonstrated. Thermal energy and electric charge of each nucleotide were set to unity and the corresponding electric field was of order 10⁷ V/m. Results indicated that the polynucleotide sequences could be accurately determined from analyzing several time series of current variation through nanopore.

Original language	English
Pages (from-to)	1308-1310
Number of pages	3
Journal	Applied Physics Letters
Volume	82
Issue number	8
DOIs	https://doi.org/10.1063/1.1554480
Publication status	Published - 2003 Feb 24

ASJC Scopus subject areas

Physics and Astronomy (miscellaneous)

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10.1063/1.1554480

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abstract = "A method to control the translocation processes of polynucleotides through a nanopore, assisted by a rotating electric field was demonstrated. Thermal energy and electric charge of each nucleotide were set to unity and the corresponding electric field was of order 107 V/m. Results indicated that the polynucleotide sequences could be accurately determined from analyzing several time series of current variation through nanopore.",

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AB - A method to control the translocation processes of polynucleotides through a nanopore, assisted by a rotating electric field was demonstrated. Thermal energy and electric charge of each nucleotide were set to unity and the corresponding electric field was of order 107 V/m. Results indicated that the polynucleotide sequences could be accurately determined from analyzing several time series of current variation through nanopore.

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Nanopore sequencing of polynucleotides assisted by a rotating electric field

Abstract

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