Nanomagnetic particles for SQUID-based magnetically labeled immunoassay

H. E. Horng; S. Y. Yang; Y. W. Huang; W. Q. Jiang; C. Y. Hong; H. C. Yang

doi:10.1109/TASC.2005.849995

Nanomagnetic particles for SQUID-based magnetically labeled immunoassay

H. E. Horng, S. Y. Yang, Y. W. Huang, W. Q. Jiang, C. Y. Hong, H. C. Yang

Graduate Institute of Electro-Optical Science And Technology

Research output: Contribution to journal › Article

35 Citations (Scopus)

Abstract

With the increasing importance of SQUID-based magnetically labeled immunoassay, the study on the synthesis of controllable sizes of magnetic nanoparticles plays a role to promote the accuracy of the immunoassay. In this work, Fe₃O₄ nano-particles coated with a suitable bio-probe (biotin) are synthesized through chemical co-precipitation process to probe the bio-target (avidin). Through the synthesis developed here, the particle hydrodynamic diameter can be adjusted from 30 to 90 nm, which provide candidates for probing various bio-targets in the future. The amount of the magnetically labeled avidin is then analyzed via measuring the saturated magnetization or the remanence of the sample by using a SQUID magnetometer.

Original language	English
Pages (from-to)	668-671
Number of pages	4
Journal	IEEE Transactions on Applied Superconductivity
Volume	15
Issue number	2 PART I
DOIs	https://doi.org/10.1109/TASC.2005.849995
Publication status	Published - 2005 Jun 1

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Keywords

Immunoassay
Nanomagnetic particles
SQUIDs

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Condensed Matter Physics
Electrical and Electronic Engineering

Cite this

Horng, H. E., Yang, S. Y., Huang, Y. W., Jiang, W. Q., Hong, C. Y., & Yang, H. C. (2005). Nanomagnetic particles for SQUID-based magnetically labeled immunoassay. IEEE Transactions on Applied Superconductivity, 15(2 PART I), 668-671. https://doi.org/10.1109/TASC.2005.849995

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10.1109/TASC.2005.849995