Nanomagnetic particles for SQUID-based magnetically labeled immunoassay

H. E. Horng; S. Y. Yang; Y. W. Huang; W. Q. Jiang; C. Y. Hong; H. C. Yang

doi:10.1109/TASC.2005.849995

Nanomagnetic particles for SQUID-based magnetically labeled immunoassay

H. E. Horng, S. Y. Yang, Y. W. Huang, W. Q. Jiang, C. Y. Hong, H. C. Yang

Graduate Institute of Electro-Optical Science And Technology

Research output: Contribution to journal › Article

35 Citations (Scopus)

Abstract

With the increasing importance of SQUID-based magnetically labeled immunoassay, the study on the synthesis of controllable sizes of magnetic nanoparticles plays a role to promote the accuracy of the immunoassay. In this work, Fe₃O₄ nano-particles coated with a suitable bio-probe (biotin) are synthesized through chemical co-precipitation process to probe the bio-target (avidin). Through the synthesis developed here, the particle hydrodynamic diameter can be adjusted from 30 to 90 nm, which provide candidates for probing various bio-targets in the future. The amount of the magnetically labeled avidin is then analyzed via measuring the saturated magnetization or the remanence of the sample by using a SQUID magnetometer.

Original language	English
Pages (from-to)	668-671
Number of pages	4
Journal	IEEE Transactions on Applied Superconductivity
Volume	15
Issue number	2 PART I
DOIs	https://doi.org/10.1109/TASC.2005.849995
Publication status	Published - 2005 Jun 1

Keywords

Immunoassay
Nanomagnetic particles
SQUIDs

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Condensed Matter Physics
Electrical and Electronic Engineering

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Horng, H. E., Yang, S. Y., Huang, Y. W., Jiang, W. Q., Hong, C. Y., & Yang, H. C. (2005). Nanomagnetic particles for SQUID-based magnetically labeled immunoassay. IEEE Transactions on Applied Superconductivity, 15(2 PART I), 668-671. https://doi.org/10.1109/TASC.2005.849995

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