Multi-target effects of novel synthetic coumarin derivatives protecting aβ-gfp sh-sy5y cells against aβ toxicity

Neuroscience

• Coumarin 100%
• Alzheimer's Disease 100%
• Kinase 75%
• Tropomyosin 75%
• Neurotoxicity 50%
• Protein Kinase B 50%
• Brain-Derived Neurotrophic Factor 50%
• Oxidative Stress 50%
• Caspase 1 50%
• Acetylcholinesterase 50%
• Neurodegenerative Disorder 25%
• Neuroprotection 25%
• Neuroprotective Agent 25%
• Memory Disorder 25%
• Cognitive Disorders 25%
• Extracellular Signal-Regulated Kinases 25%
• Neuroblastoma 25%
• Cyclic Adenosine Monophosphate 25%
• Response Element 25%
• Neurite Outgrowth 25%
• Amyloid Protein 25%
• Protein Binding 25%
• B Cell 25%
• Blood Brain Barrier 25%
• Membrane Permeability 25%
• Protein Serine Threonine Kinase 25%
• Receptor Affinity 25%

Pharmacology, Toxicology and Pharmaceutical Science

• Coumarin Derivative 100%
• Alzheimer's Disease 100%
• Tropomyosin 75%
• Phosphotransferase 75%
• Neurotoxicity 50%
• Interleukin 1beta Converting Enzyme 50%
• Brain Derived Neurotrophic Factor 50%
• Acetylcholinesterase 50%
• Protein Kinase B 50%
• Antiapoptotic 25%
• Binding Protein 25%
• Neuroprotection 25%
• Parallel Artificial Membrane Permeability Assay 25%
• Receptor 25%
• Mitogen Activated Protein Kinase 25%
• Cognitive Defect 25%
• Degenerative Disease 25%
• Neuroprotective Agent 25%
• Amyloid Protein 25%
• B Cell Lymphoma 25%
• Neuroblastoma 25%
• Memory Disorder 25%
• Blood-Brain Barrier 25%
• Protein Serine Threonine Kinase 25%

INIS

• nervous system diseases 100%
• kinases 100%
• toxicity 100%
• coumarin 100%
• tropomyosin 60%
• oxidation 40%
• brain 40%
• aggregation 40%
• zinc compounds 40%
• increasing 20%
• signals 20%
• proteins 20%
• receptors 20%
• membranes 20%
• affinity 20%
• inhibition 20%
• blood-brain barrier 20%
• permeability 20%
• lymphomas 20%
• serine 20%
• threonine 20%