@inproceedings{dcc1198525bc46af81917880031a0d27,
title = "Multi-functional stage-scanning fluorescence micro/nanoscope for single-lipid dynamics",
abstract = "We combine pulsed laser, supercontinuum radiation source and fast single-photon counting peripherals to obtain a multifunctional micro/nano-scope. This provides us with better spatial and temporal resolution to observe fast dynamics. Performing fluorescence correlation spectroscopy for fast dynamics (<μs) with sub-diffraction limit resolution to observe the initial state of single-lipid dynamics in supported lipid bilayers and living cells is our goal. Lipid raft serves as a platform for recruiting signaling components of effective signal transduction. However, the dynamics of sub-200nm rapidly aggregated lipid rafts are still not elucidated in living cells. We here report our recent progress on the construction of this multi-functional stage-scanning fluorescence micro/nanoscope for single-lipid dynamics study.",
author = "Yang, \{Li Ling\} and Hsieh, \{Chia Fen\} and Chang, \{Yi Ren\} and Shen, \{Jie Pan\} and Chang, \{Yu Chung\} and Chou, \{Chia Fu\}",
year = "2012",
doi = "10.1117/12.908179",
language = "English",
isbn = "9780819488718",
series = "Progress in Biomedical Optics and Imaging - Proceedings of SPIE",
booktitle = "Single Molecule Spectroscopy and Superresolution Imaging V",
note = "Single Molecule Spectroscopy and Superresolution Imaging V ; Conference date: 21-01-2012 Through 22-01-2012",
}