Monitoring the transdermal delivery of fluorescent nanoparticles using multiphoton fluorescence microscopy

Chien Hsin Tso, Wen Lo, Pei Yue Huang, Tze Lung Hsu, Chun Chai Yeh, Sung Jan Lin, Shiou Hwa Jee, Chia Chun Chen*, Chen Yuan Dong

*Corresponding author for this work

Research output: Contribution to journalConference articlepeer-review


An interesting area of applying multiphoton fluorescence microscopy is in investigating the delivery of fluorescent nanoparticles (quantum dots) across biological barriers such as the skin. Fluorescence nanoparticles are nanometer in size and understanding the delivery mechanisms of these materials across the skin can be important in understanding the delivery of important biological macromolecules for therapeutic purposes. In addition, pathological diagnosis can be performed with the successful delivery of fluorescent nanoparticles.

Original languageEnglish
Pages (from-to)360-364
Number of pages5
JournalProceedings of SPIE - The International Society for Optical Engineering
Publication statusPublished - 2004
EventProgress in Biomedical Optics and Imaging - Multiphoton Microscopy in the Biomedical Sciences IV - San Jose, CA, United States
Duration: 2004 Jan 252004 Jan 27


  • Multiphoton microscopy
  • Quantum dots
  • Transdermal delivery

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering


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